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ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MLKCICRVYS QPLAQMVTSP LFKHMGSAGT YTILPITNLR HLSTKNCPLK IKSNRSEPLQ

70 80 90 100 110 120
FGDFERQVPC SRKSGSSKNV QKRLYELRQL KTVLSETFGV TEYASFFESL RNALHINNCS

130 140 150 160 170 180
ENEKKKLLYD IILHQHELYP EVARKIGFYL PGEVHRWFWY HIPKSESFNH YLFLLKSDVL

190 200 210 220 230 240
LFTSNYCTRF TNRLIKGTEM ERQLATFQIF LHDETNIKFI MEKVLKLHTF DSLIALVNGL

250 260 270 280 290 300
VKAKNFRFIK VFIQALLQKL EQHCYSGKDG AKQKNLRYVK FNNTLLYYLL KSGNVELFIK

310 320 330 340 350 360
TFQEELKFIV SSGLLNHIDG NEHILNFPIH HYLNLLRISN RQEELFNVIS CLQSSPLMKY

370 380 390 400 410 420
KLFKEFLMGE LIASFQAFRD PKLVCKYLLS SYSSKASANI LNALGIWGWL YHSKSTTLTA

430 440 450 460 470 480
PTLARELKNK NNILPNTMRI GSPVTVPILT ELYRSLLSSS SVSLESGQFK NCLLDLYYKY

490 500 510 520 530 540
KSFLSEEAHK YRYWRNDTGI LNVFLNYIRF QAREPRLAYN VLLDFYSQPF AKKVVLTTTL

550 560 570 580 590 600
CPFSIVAYKN HTLTQAELSE LLQVMHKNGV PLTFKFCSAM VMHYVKMRDE KEHAPGTIRY

610
SSGALKSGIW L


References and documentation are available.

Number of amino acids: 611 Molecular weight: 71015.79 Theoretical pI: 9.55
Amino acid composition: 
Ala (A) 26 4.3% Arg (R) 28 4.6% Asn (N) 37 6.1% Asp (D) 12 2.0% Cys (C) 12 2.0% Gln (Q) 22 3.6% Glu (E) 35 5.7% Gly (G) 24 3.9% His (H) 21 3.4% Ile (I) 34 5.6% Leu (L) 87 14.2% Lys (K) 51 8.3% Met (M) 12 2.0% Phe (F) 38 6.2% Pro (P) 21 3.4% Ser (S) 52 8.5% Thr (T) 32 5.2% Trp (W) 6 1.0% Tyr (Y) 31 5.1% Val (V) 30 4.9% Pyl (O) 0 0.0% Sec (U) 0 0.0% (B) 0 0.0% (Z) 0 0.0% (X) 0 0.0%
Total number of negatively charged residues (Asp + Glu): 47 Total number of positively charged residues (Arg + Lys): 79 Atomic composition: Carbon C 3255 Hydrogen H 5083 Nitrogen N 853 Oxygen O 880 Sulfur S 24 Formula: C3255H5083N853O880S24 Total number of atoms: 10095 Extinction coefficients: Extinction coefficients are in units of M-1 cm-1, at 280 nm measured in water. Ext. coefficient 79940 Abs 0.1% (=1 g/l) 1.126, assuming all pairs of Cys residues form cystines Ext. coefficient 79190 Abs 0.1% (=1 g/l) 1.115, assuming all Cys residues are reduced Estimated half-life: The N-terminal of the sequence considered is M (Met). The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro). >20 hours (yeast, in vivo). >10 hours (Escherichia coli, in vivo). Instability index: The instability index (II) is computed to be 44.49 This classifies the protein as unstable. Aliphatic index: 95.73 Grand average of hydropathicity (GRAVY): -0.164