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ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MLKVPLSDVL SQKMLFLKSF RYFHCTKYFS RDNASSTTDI FRNAMKRKRE LANLKEQSHG

70 80 90 100 110 120
NVARNAAFPK EYIKRPKQVP RNATNRKKIL ITWSTGTDRA KEAANSVVSE IFKKNHKGNI

130 140 150 160 170 180
KVVDPTTHRI EASNIRYFAK GIDLDKVGLS IVNVEQIDNE NQIPLVKIVE SRVALKKYSD

190 200 210 220 230 240
FLAKKKEKEL MELGVLNKSY KNLVTDKKED NLKHIKISWQ IESDDLKRQK AHEIVSLLKK

250 260 270 280 290 300
GNKVTLYLDD KNNINSNNWL ENFEELDRSQ KGEPPRLPES VFQKRAAVLE TLKEIVSEYA

310 320 330 340 350
NDPVLLGNMN SKMIMKLIPK DVKPQNNDKR ALKELRKKER QEKLQKRIQR KKMNEM


References and documentation are available.

Number of amino acids: 356 Molecular weight: 41461.09 Theoretical pI: 9.90
Amino acid composition: 
Ala (A) 19 5.3% Arg (R) 22 6.2% Asn (N) 30 8.4% Asp (D) 19 5.3% Cys (C) 1 0.3% Gln (Q) 13 3.7% Glu (E) 27 7.6% Gly (G) 9 2.5% His (H) 6 1.7% Ile (I) 22 6.2% Leu (L) 34 9.6% Lys (K) 53 14.9% Met (M) 9 2.5% Phe (F) 11 3.1% Pro (P) 12 3.4% Ser (S) 23 6.5% Thr (T) 12 3.4% Trp (W) 3 0.8% Tyr (Y) 8 2.2% Val (V) 23 6.5% Pyl (O) 0 0.0% Sec (U) 0 0.0% (B) 0 0.0% (Z) 0 0.0% (X) 0 0.0%
Total number of negatively charged residues (Asp + Glu): 46 Total number of positively charged residues (Arg + Lys): 75 Atomic composition: Carbon C 1837 Hydrogen H 3027 Nitrogen N 533 Oxygen O 535 Sulfur S 10 Formula: C1837H3027N533O535S10 Total number of atoms: 5942 Extinction coefficients: Extinction coefficients are in units of M-1 cm-1, at 280 nm measured in water. Ext. coefficient 28420 Abs 0.1% (=1 g/l) 0.685, assuming all pairs of Cys residues form cystines Ext. coefficient 28420 Abs 0.1% (=1 g/l) 0.685, assuming all Cys residues are reduced Estimated half-life: The N-terminal of the sequence considered is M (Met). The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro). >20 hours (yeast, in vivo). >10 hours (Escherichia coli, in vivo). Instability index: The instability index (II) is computed to be 37.34 This classifies the protein as stable. Aliphatic index: 85.42 Grand average of hydropathicity (GRAVY): -0.814