ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MLLGKFLLVA SFILPIAYTW TGATIRNHPA DVVAARNKIT SRSVARSEPT NSYIRPCYFT 

        70         80         90        100        110        120 
NWAQYRQGRA KFVPEDYTPG LCTHILFAFG WMNADYTVRA YDPADLPNDW AGEGMYRRVN 

       130        140        150        160        170        180 
KLKVTDTQLK TLLSFGGWSF GTALFQGMAA SSASRKVFID SAITFVRTWG FDGIDIDWEY 

       190        200        210        220        230        240 
PSGATDMANY VALVKELKAA CESEAGSTGK DRLLVTAAVA AGPATIDAGY DIPNLAPNFD 

       250        260        270        280        290        300 
FILLMSYDFF GAWASLVGFN SPLYATTELP AEWNGWNVDS SARYWNQKGM PKEKIIVGMP 

       310        320        330        340        350        360 
TYGRGWTLNN ASAINPGTSG SPAKITQYVQ EAGVGAYFEF CEMLANGATR YWDSQSQVPY 

       370        380        390        400        410        420 
LVQGNQWWSY DDEESFANKM AYVKREGYGG AFVWTLDFDD FNAGCSNSNG QLYPLISVIA 

       430        440        450        460        470        480 
KELGGVIIPK KGGVTTAPTT VATTVTTGRP PMTSAVTTTT AATTTTTRAA TTTTASNTNV 

       490        500        510        520        530        540 
CSGKSDGFYP NSNNCGLFVL CLSSKSYSMS CPSGLQYSAS LKYCTTSTAS GCSVTTTRAP 

       550        560        570        580        590        600 
TTTTKSAPTV TTTTRAPTTT TPAFKCTKDG FFGVPSDCLK FIRCVNGISY NFECPNGLSF 

       610 
HADTMMCDRP DPSKCAK 

References and documentation are available.

Number of amino acids: 617

Molecular weight: 66857.41

Theoretical pI: 8.01

Amino acid composition: 
Ala (A)  65	 10.5%
Arg (R)  23	  3.7%
Asn (N)  31	  5.0%
Asp (D)  30	  4.9%
Cys (C)  17	  2.8%
Gln (Q)  13	  2.1%
Glu (E)  18	  2.9%
Gly (G)  50	  8.1%
His (H)   3	  0.5%
Ile (I)  23	  3.7%
Leu (L)  37	  6.0%
Lys (K)  28	  4.5%
Met (M)  14	  2.3%
Phe (F)  31	  5.0%
Pro (P)  34	  5.5%
Ser (S)  50	  8.1%
Thr (T)  71	 11.5%
Trp (W)  16	  2.6%
Tyr (Y)  28	  4.5%
Val (V)  35	  5.7%
Pyl (O)   0	  0.0%
Sec (U)   0	  0.0%

 (B)   0	  0.0%
 (Z)   0	  0.0%
 (X)   0	  0.0%


Total number of negatively charged residues (Asp + Glu): 48
Total number of positively charged residues (Arg + Lys): 51

Atomic composition:

Carbon      C	      2985
Hydrogen    H	      4538
Nitrogen    N	       780
Oxygen      O	       907
Sulfur      S	        31

Formula: C2985H4538N780O907S31
Total number of atoms: 9241

Extinction coefficients:

Extinction coefficients are in units of  M-1 cm-1, at 280 nm measured in water.

Ext. coefficient   130720
Abs 0.1% (=1 g/l)   1.955, assuming all pairs of Cys residues form cystines


Ext. coefficient   129720
Abs 0.1% (=1 g/l)   1.940, assuming all Cys residues are reduced

Estimated half-life:

The N-terminal of the sequence considered is M (Met).

The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro).
                            >20 hours (yeast, in vivo).
                            >10 hours (Escherichia coli, in vivo).


Instability index:

The instability index (II) is computed to be 31.92
This classifies the protein as stable.



Aliphatic index: 64.91

Grand average of hydropathicity (GRAVY): -0.154