ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MLMHFIPRRS SKAVQFNWLE IGVWRGGVYV KKGIVNARTN NSNFYKMPVV FGIVKGMGAL 

        70         80         90        100        110        120 
CVHAWGMGYG GIIDCSPVTE HGNISVLQLE YMPWICLSKI MSCSVASRHS NVWIMDETIA 


PLVGCL 

References and documentation are available.

Number of amino acids: 126

Molecular weight: 14021.61

Theoretical pI: 9.12

Amino acid composition: 
Ala (A)   6	  4.8%
Arg (R)   5	  4.0%
Asn (N)   7	  5.6%
Asp (D)   2	  1.6%
Cys (C)   5	  4.0%
Gln (Q)   2	  1.6%
Glu (E)   4	  3.2%
Gly (G)  13	 10.3%
His (H)   4	  3.2%
Ile (I)  11	  8.7%
Leu (L)   8	  6.3%
Lys (K)   6	  4.8%
Met (M)   8	  6.3%
Phe (F)   4	  3.2%
Pro (P)   5	  4.0%
Ser (S)  10	  7.9%
Thr (T)   3	  2.4%
Trp (W)   5	  4.0%
Tyr (Y)   4	  3.2%
Val (V)  14	 11.1%
Pyl (O)   0	  0.0%
Sec (U)   0	  0.0%

 (B)   0	  0.0%
 (Z)   0	  0.0%
 (X)   0	  0.0%


Total number of negatively charged residues (Asp + Glu): 6
Total number of positively charged residues (Arg + Lys): 11

Atomic composition:

Carbon      C	       633
Hydrogen    H	       987
Nitrogen    N	       169
Oxygen      O	       165
Sulfur      S	        13

Formula: C633H987N169O165S13
Total number of atoms: 1967

Extinction coefficients:

Extinction coefficients are in units of  M-1 cm-1, at 280 nm measured in water.

Ext. coefficient    33710
Abs 0.1% (=1 g/l)   2.404, assuming all pairs of Cys residues form cystines


Ext. coefficient    33460
Abs 0.1% (=1 g/l)   2.386, assuming all Cys residues are reduced

Estimated half-life:

The N-terminal of the sequence considered is M (Met).

The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro).
                            >20 hours (yeast, in vivo).
                            >10 hours (Escherichia coli, in vivo).


Instability index:

The instability index (II) is computed to be 52.31
This classifies the protein as unstable.



Aliphatic index: 95.79

Grand average of hydropathicity (GRAVY): 0.351