ProtParam
User-provided sequence:
10 20 30 40 50 60
MLMHFIPRRS SKAVQFNWLE IGVWRGGVYV KKGIVNARTN NSNFYKMPVV FGIVKGMGAL
70 80 90 100 110 120
CVHAWGMGYG GIIDCSPVTE HGNISVLQLE YMPWICLSKI MSCSVASRHS NVWIMDETIA
PLVGCL
References and
documentation are available.
Number of amino acids: 126
Molecular weight: 14021.61
Theoretical pI: 9.12
Total number of negatively charged residues (Asp + Glu): 6
Total number of positively charged residues (Arg + Lys): 11
Atomic composition:
Carbon C 633
Hydrogen H 987
Nitrogen N 169
Oxygen O 165
Sulfur S 13
Formula: C
633H
987N
169O
165S
13
Total number of atoms: 1967
Extinction coefficients:
Extinction coefficients are in units of M
-1 cm
-1, at 280 nm measured in water.
Ext. coefficient 33710
Abs 0.1% (=1 g/l) 2.404, assuming all pairs of Cys residues form cystines
Ext. coefficient 33460
Abs 0.1% (=1 g/l) 2.386, assuming all Cys residues are reduced
Estimated half-life:
The N-terminal of the sequence considered is M (Met).
The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro).
>20 hours (yeast, in vivo).
>10 hours (Escherichia coli, in vivo).
Instability index:
The instability index (II) is computed to be 52.31
This classifies the protein as unstable.
Aliphatic index: 95.79
Grand average of hydropathicity (GRAVY): 0.351