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ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MLMPKQERNK IHQYLFQEGV VVAKKDFNQA KHEEIDTKNL YVIKALQSLT SKGYVKTQFS

70 80 90 100
WQYYYYTLTE EGVEYLREYL NLPEHIVPGT YIQERNPSQR PQRRY


References and documentation are available.

Number of amino acids: 105 Molecular weight: 12738.48 Theoretical pI: 9.05
Amino acid composition: 
Ala (A) 3 2.9% Arg (R) 6 5.7% Asn (N) 5 4.8% Asp (D) 2 1.9% Cys (C) 0 0.0% Gln (Q) 10 9.5% Glu (E) 10 9.5% Gly (G) 4 3.8% His (H) 3 2.9% Ile (I) 5 4.8% Leu (L) 9 8.6% Lys (K) 9 8.6% Met (M) 2 1.9% Phe (F) 3 2.9% Pro (P) 5 4.8% Ser (S) 4 3.8% Thr (T) 6 5.7% Trp (W) 1 1.0% Tyr (Y) 11 10.5% Val (V) 7 6.7% Pyl (O) 0 0.0% Sec (U) 0 0.0% (B) 0 0.0% (Z) 0 0.0% (X) 0 0.0%
Total number of negatively charged residues (Asp + Glu): 12 Total number of positively charged residues (Arg + Lys): 15 Atomic composition: Carbon C 580 Hydrogen H 888 Nitrogen N 154 Oxygen O 166 Sulfur S 2 Formula: C580H888N154O166S2 Total number of atoms: 1790 Extinction coefficients: Extinction coefficients are in units of M-1 cm-1, at 280 nm measured in water. Ext. coefficient 21890 Abs 0.1% (=1 g/l) 1.718 Estimated half-life: The N-terminal of the sequence considered is M (Met). The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro). >20 hours (yeast, in vivo). >10 hours (Escherichia coli, in vivo). Instability index: The instability index (II) is computed to be 59.07 This classifies the protein as unstable. Aliphatic index: 74.19 Grand average of hydropathicity (GRAVY): -0.902