ProtParam
User-provided sequence:
10 20 30 40 50 60
MLNYKLILLF SSFLQLISFS GFMICCLTSP IIRNWGLAQA AGVSYGTFGY CKTLNSFSCS
70 80 90 100 110 120
RVRLIYNTSK EILPGPSLER WWLSPKARHT IGGLLISIPV ATCLTFISFA LPLVIIFLFQ
130 140 150 160 170 180
TGGTNVSLIT SNAILHILTL LSTIFACTVI LLLCMHRDPV TISSLYDLVW LANCSLFPLL
190 200
VIGVHFLSFR FDTSAQSDRK HS
References and
documentation are available.
Number of amino acids: 202
Molecular weight: 22434.68
Theoretical pI: 9.16
Total number of negatively charged residues (Asp + Glu): 6
Total number of positively charged residues (Arg + Lys): 13
Atomic composition:
Carbon C 1043
Hydrogen H 1636
Nitrogen N 256
Oxygen O 270
Sulfur S 11
Formula: C
1043H
1636N
256O
270S
11
Total number of atoms: 3216
Extinction coefficients:
Extinction coefficients are in units of M
-1 cm
-1, at 280 nm measured in water.
Ext. coefficient 29950
Abs 0.1% (=1 g/l) 1.335, assuming all pairs of Cys residues form cystines
Ext. coefficient 29450
Abs 0.1% (=1 g/l) 1.313, assuming all Cys residues are reduced
Estimated half-life:
The N-terminal of the sequence considered is M (Met).
The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro).
>20 hours (yeast, in vivo).
>10 hours (Escherichia coli, in vivo).
Instability index:
The instability index (II) is computed to be 48.75
This classifies the protein as unstable.
Aliphatic index: 123.56
Grand average of hydropathicity (GRAVY): 0.787