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ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MLPEKRLLTP DDMKLWEESP TRAHFTKFII DLAESVKGHE NSQYKEPISE SINSMMNLLS

70 80 90 100 110 120
QIKDITQKHP VIKDADSSRF GKVEFRDFYD EVSRNSRKIL RSEFPSLTDE QLEQLSIYLD

130 140 150 160 170 180
ESWGNKRRID YGSGHELNFM CLLYGLYSYG IFNLSNDSTN LVLKVFIEYL KIMRILETKY

190 200 210 220 230 240
WLEPAGSHGV WGLDDYHFLP FLFGAFQLTT HKHLKPISIH NNELVEMFAH RYLYFGCIAF

250 260 270 280 290 300
INKVKSSASL RWHSPMLDDI SGVKTWSKVA EGMIKMYKAE VLSKLPIMQH FYFSEFLPCP

310 320 330 340 350
DGVSPPRGHI HDGTDKDDEC NFEGHVHTTW GDCCGIKLPS AIAATEMNKK HHKPIPFD


References and documentation are available.

Number of amino acids: 358 Molecular weight: 41452.45 Theoretical pI: 6.22
Amino acid composition: 
Ala (A) 13 3.6% Arg (R) 13 3.6% Asn (N) 14 3.9% Asp (D) 23 6.4% Cys (C) 6 1.7% Gln (Q) 7 2.0% Glu (E) 25 7.0% Gly (G) 20 5.6% His (H) 18 5.0% Ile (I) 25 7.0% Leu (L) 35 9.8% Lys (K) 28 7.8% Met (M) 12 3.4% Phe (F) 21 5.9% Pro (P) 18 5.0% Ser (S) 31 8.7% Thr (T) 14 3.9% Trp (W) 7 2.0% Tyr (Y) 14 3.9% Val (V) 14 3.9% Pyl (O) 0 0.0% Sec (U) 0 0.0% (B) 0 0.0% (Z) 0 0.0% (X) 0 0.0%
Total number of negatively charged residues (Asp + Glu): 48 Total number of positively charged residues (Arg + Lys): 41 Atomic composition: Carbon C 1880 Hydrogen H 2863 Nitrogen N 489 Oxygen O 535 Sulfur S 18 Formula: C1880H2863N489O535S18 Total number of atoms: 5785 Extinction coefficients: Extinction coefficients are in units of M-1 cm-1, at 280 nm measured in water. Ext. coefficient 59735 Abs 0.1% (=1 g/l) 1.441, assuming all pairs of Cys residues form cystines Ext. coefficient 59360 Abs 0.1% (=1 g/l) 1.432, assuming all Cys residues are reduced Estimated half-life: The N-terminal of the sequence considered is M (Met). The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro). >20 hours (yeast, in vivo). >10 hours (Escherichia coli, in vivo). Instability index: The instability index (II) is computed to be 42.72 This classifies the protein as unstable. Aliphatic index: 80.34 Grand average of hydropathicity (GRAVY): -0.387