ProtParam
User-provided sequence:
10 20 30 40 50 60
MLPLYLLTNA KGQQMQIELK NGEIIQGILT NVDNWMNLTL SNVTEYSEES AINSEDNAES
70 80 90 100 110 120
SKAVKLNEIY IRGTFIKFIK LQDNIIDKVK QQINSNNNSN SNGPGHKRYY NNRDSNNNRG
130 140 150 160 170 180
NYNRRNNNNG NSNRRPYSQN RQYNNSNSSN INNSINSINS NNQNMNNGLG GSVQHHFNSS
SPQKVEF
References and
documentation are available.
Number of amino acids: 187
Molecular weight: 21276.12
Theoretical pI: 9.45
Total number of negatively charged residues (Asp + Glu): 14
Total number of positively charged residues (Arg + Lys): 19
Atomic composition:
Carbon C 898
Hydrogen H 1419
Nitrogen N 287
Oxygen O 307
Sulfur S 4
Formula: C
898H
1419N
287O
307S
4
Total number of atoms: 2915
Extinction coefficients:
Extinction coefficients are in units of M
-1 cm
-1, at 280 nm measured in water.
Ext. coefficient 17420
Abs 0.1% (=1 g/l) 0.819
Estimated half-life:
The N-terminal of the sequence considered is M (Met).
The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro).
>20 hours (yeast, in vivo).
>10 hours (Escherichia coli, in vivo).
Instability index:
The instability index (II) is computed to be 43.48
This classifies the protein as unstable.
Aliphatic index: 65.67
Grand average of hydropathicity (GRAVY): -1.159