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ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MLPLYLLTNA KGQQMQIELK NGEIIQGILT NVDNWMNLTL SNVTEYSEES AINSEDNAES

70 80 90 100 110 120
SKAVKLNEIY IRGTFIKFIK LQDNIIDKVK QQINSNNNSN SNGPGHKRYY NNRDSNNNRG

130 140 150 160 170 180
NYNRRNNNNG NSNRRPYSQN RQYNNSNSSN INNSINSINS NNQNMNNGLG GSVQHHFNSS


SPQKVEF


References and documentation are available.

Number of amino acids: 187 Molecular weight: 21276.12 Theoretical pI: 9.45
Amino acid composition: 
Ala (A) 4 2.1% Arg (R) 9 4.8% Asn (N) 44 23.5% Asp (D) 5 2.7% Cys (C) 0 0.0% Gln (Q) 12 6.4% Glu (E) 9 4.8% Gly (G) 11 5.9% His (H) 3 1.6% Ile (I) 15 8.0% Leu (L) 11 5.9% Lys (K) 10 5.3% Met (M) 4 2.1% Phe (F) 4 2.1% Pro (P) 4 2.1% Ser (S) 22 11.8% Thr (T) 5 2.7% Trp (W) 1 0.5% Tyr (Y) 8 4.3% Val (V) 6 3.2% Pyl (O) 0 0.0% Sec (U) 0 0.0% (B) 0 0.0% (Z) 0 0.0% (X) 0 0.0%
Total number of negatively charged residues (Asp + Glu): 14 Total number of positively charged residues (Arg + Lys): 19 Atomic composition: Carbon C 898 Hydrogen H 1419 Nitrogen N 287 Oxygen O 307 Sulfur S 4 Formula: C898H1419N287O307S4 Total number of atoms: 2915 Extinction coefficients: Extinction coefficients are in units of M-1 cm-1, at 280 nm measured in water. Ext. coefficient 17420 Abs 0.1% (=1 g/l) 0.819 Estimated half-life: The N-terminal of the sequence considered is M (Met). The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro). >20 hours (yeast, in vivo). >10 hours (Escherichia coli, in vivo). Instability index: The instability index (II) is computed to be 43.48 This classifies the protein as unstable. Aliphatic index: 65.67 Grand average of hydropathicity (GRAVY): -1.159