ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MLQGFLFLLS VVLLFSSSAA ACDRCLHSSK AAYFSSASAL SSGACAYGSM ATGFFAGHIA 

        70         80         90        100        110        120 
AALPSIYKDG SGCGACFQVR CKNPTLCSSK GTTVIVTDLN KTNQTDLVLS SRAFRAMAKP 

       130        140        150        160        170        180 
VVGADRDLLK QGIVDIEYRR VPCDYGNKKM NVRVEESSKN PNYLAIKLLY QGGQTEVVAI 

       190        200        210        220        230        240 
YIAQVGSSHW SYMTRSHGAV WVTDKVPNGA LQFRFVVTAG YDGKMVWSQR VLPANWEAGK 

       250        260 
SYDAGVQITD IAQEGCDPCD DHIWN 

References and documentation are available.

Number of amino acids: 265

Molecular weight: 28642.68

Theoretical pI: 8.48

Amino acid composition: 
Ala (A)  29	 10.9%
Arg (R)  11	  4.2%
Asn (N)  10	  3.8%
Asp (D)  15	  5.7%
Cys (C)  10	  3.8%
Gln (Q)  11	  4.2%
Glu (E)   6	  2.3%
Gly (G)  22	  8.3%
His (H)   5	  1.9%
Ile (I)  11	  4.2%
Leu (L)  20	  7.5%
Lys (K)  14	  5.3%
Met (M)   6	  2.3%
Phe (F)  10	  3.8%
Pro (P)   8	  3.0%
Ser (S)  26	  9.8%
Thr (T)  12	  4.5%
Trp (W)   5	  1.9%
Tyr (Y)  11	  4.2%
Val (V)  23	  8.7%
Pyl (O)   0	  0.0%
Sec (U)   0	  0.0%

 (B)   0	  0.0%
 (Z)   0	  0.0%
 (X)   0	  0.0%


Total number of negatively charged residues (Asp + Glu): 21
Total number of positively charged residues (Arg + Lys): 25

Atomic composition:

Carbon      C	      1267
Hydrogen    H	      1974
Nitrogen    N	       348
Oxygen      O	       378
Sulfur      S	        16

Formula: C1267H1974N348O378S16
Total number of atoms: 3983

Extinction coefficients:

Extinction coefficients are in units of  M-1 cm-1, at 280 nm measured in water.

Ext. coefficient    44515
Abs 0.1% (=1 g/l)   1.554, assuming all pairs of Cys residues form cystines


Ext. coefficient    43890
Abs 0.1% (=1 g/l)   1.532, assuming all Cys residues are reduced

Estimated half-life:

The N-terminal of the sequence considered is M (Met).

The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro).
                            >20 hours (yeast, in vivo).
                            >10 hours (Escherichia coli, in vivo).


Instability index:

The instability index (II) is computed to be 41.36
This classifies the protein as unstable.



Aliphatic index: 81.74

Grand average of hydropathicity (GRAVY): 0.008