ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MLQRHSLKLG KFSIRTLATG APLDASKLKI TRNPNPSKPR PNEELVFGQT FTDHMLTIPW 

        70         80         90        100        110        120 
SAKEGWGTPH IKPYGNLSLD PSACVFHYAF ELFEGLKAYR TPQNTITMFR PDKNMARMNK 

       130        140        150        160        170        180 
SAARICLPTF ESEELIKLTG KLIEQDKHLV PQGNGYSLYI RPTMIGTSKG LGVGTPSEAL 

       190        200        210        220        230        240 
LYVITSPVGP YYKTGFKAVR LEATDYATRA WPGGVGDKKL GANYAPCILP QLQAAKRGYQ 

       250        260        270        280        290        300 
QNLWLFGPEK NITEVGTMNV FFVFLNKVTG KKELVTAPLD GTILEGVTRD SVLTLARDKL 

       310        320        330        340        350        360 
DPQEWDINER YYTITEVATR AKQGELLEAF GSGTAAVVSP IKEIGWNNED IHVPLLPGEQ 

       370        380        390 
CGALTKQVAQ WIADIQYGRV NYGNWSKTVA DLN 

References and documentation are available.

Number of amino acids: 393

Molecular weight: 43596.06

Theoretical pI: 9.01

Amino acid composition: 
Ala (A)  30	  7.6%
Arg (R)  17	  4.3%
Asn (N)  19	  4.8%
Asp (D)  15	  3.8%
Cys (C)   4	  1.0%
Gln (Q)  15	  3.8%
Glu (E)  23	  5.9%
Gly (G)  34	  8.7%
His (H)   6	  1.5%
Ile (I)  21	  5.3%
Leu (L)  40	 10.2%
Lys (K)  28	  7.1%
Met (M)   7	  1.8%
Phe (F)  14	  3.6%
Pro (P)  26	  6.6%
Ser (S)  17	  4.3%
Thr (T)  32	  8.1%
Trp (W)   8	  2.0%
Tyr (Y)  15	  3.8%
Val (V)  22	  5.6%
Pyl (O)   0	  0.0%
Sec (U)   0	  0.0%

 (B)   0	  0.0%
 (Z)   0	  0.0%
 (X)   0	  0.0%


Total number of negatively charged residues (Asp + Glu): 38
Total number of positively charged residues (Arg + Lys): 45

Atomic composition:

Carbon      C	      1971
Hydrogen    H	      3090
Nitrogen    N	       526
Oxygen      O	       568
Sulfur      S	        11

Formula: C1971H3090N526O568S11
Total number of atoms: 6166

Extinction coefficients:

Extinction coefficients are in units of  M-1 cm-1, at 280 nm measured in water.

Ext. coefficient    66600
Abs 0.1% (=1 g/l)   1.528, assuming all pairs of Cys residues form cystines


Ext. coefficient    66350
Abs 0.1% (=1 g/l)   1.522, assuming all Cys residues are reduced

Estimated half-life:

The N-terminal of the sequence considered is M (Met).

The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro).
                            >20 hours (yeast, in vivo).
                            >10 hours (Escherichia coli, in vivo).


Instability index:

The instability index (II) is computed to be 32.04
This classifies the protein as stable.



Aliphatic index: 84.40

Grand average of hydropathicity (GRAVY): -0.304