ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MLRNLILITL LVASGHGQTP VIGGTCKLGT ADVQIGGKQT QFFLKCETTA DSAEGEGVWV 

        70         80         90        100        110        120 
VKSRAAAAPS SVPSVPAENT QPQQHPKARK PASPNICEQD NGARESEVCA VSATCLQAHN 

       130        140        150        160        170        180 
DFPSSYLQCD QTTLRWVRKS CQENFLFNFE QQTCIVPKRM SSLSRQQASG LVCTFSSCSN 

       190        200        210        220        230        240 
SNPCSVGTCN NGYCCSSGSN SGSAIIVGGG SSNCVGCQNA PQIITIPQNS CPGGGYSVGG 

       250        260        270        280        290        300 
CSSGYCATGY SCIQNQCCPS YNSAPRISVY TCPSGGNAVG ACMSGRCASG YTCSNNVCCP 

       310        320        330        340        350        360 
QTTTTNPFVC PDGTQAAGGC VNGQCGTGYT CSNGLCCAGT STTVKCLDGS DAVGACIPSC 

       370        380        390        400        410        420 
TGDGCGGVQV SYYCGSGYTC TTGNICCPIN SCPNGGEVLG PTINGLCPTG YTVQGNLCCS 

       430        440        450        460        470        480 
ATCTDGSTGL PSVNGVCIDG YSLTNGVCCP ASVTCTDEIS IGPCTGTGFN GGCPAGYACD 

       490        500        510        520        530        540 
SNQVNCCPVV RYTDESCQVG PAIDGLCPPG YVVVYIPNSP LITNGVNPGT CIDLQCTTGL 

       550        560        570        580        590        600 
CLTANQIGDC DTATDAGTCP TGYTCFTNAG ICCSTTTFSR LRIGNSRQMA QKPNYGRPLH 

       610        620 
SYMPPFQMND DPVIDAANDD KSSSSVSV 

References and documentation are available.

Number of amino acids: 628

Molecular weight: 64136.75

Theoretical pI: 4.89

Amino acid composition: 
Ala (A)  40	  6.4%
Arg (R)  15	  2.4%
Asn (N)  42	  6.7%
Asp (D)  24	  3.8%
Cys (C)  66	 10.5%
Gln (Q)  33	  5.3%
Glu (E)  12	  1.9%
Gly (G)  77	 12.3%
His (H)   4	  0.6%
Ile (I)  28	  4.5%
Leu (L)  27	  4.3%
Lys (K)  11	  1.8%
Met (M)   6	  1.0%
Phe (F)  12	  1.9%
Pro (P)  42	  6.7%
Ser (S)  65	 10.4%
Thr (T)  58	  9.2%
Trp (W)   2	  0.3%
Tyr (Y)  21	  3.3%
Val (V)  43	  6.8%
Pyl (O)   0	  0.0%
Sec (U)   0	  0.0%

 (B)   0	  0.0%
 (Z)   0	  0.0%
 (X)   0	  0.0%


Total number of negatively charged residues (Asp + Glu): 36
Total number of positively charged residues (Arg + Lys): 26

Atomic composition:

Carbon      C	      2672
Hydrogen    H	      4211
Nitrogen    N	       769
Oxygen      O	       920
Sulfur      S	        72

Formula: C2672H4211N769O920S72
Total number of atoms: 8644

Extinction coefficients:

Extinction coefficients are in units of  M-1 cm-1, at 280 nm measured in water.

Ext. coefficient    46415
Abs 0.1% (=1 g/l)   0.724, assuming all pairs of Cys residues form cystines


Ext. coefficient    42290
Abs 0.1% (=1 g/l)   0.659, assuming all Cys residues are reduced

Estimated half-life:

The N-terminal of the sequence considered is M (Met).

The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro).
                            >20 hours (yeast, in vivo).
                            >10 hours (Escherichia coli, in vivo).


Instability index:

The instability index (II) is computed to be 41.48
This classifies the protein as unstable.



Aliphatic index: 60.38

Grand average of hydropathicity (GRAVY): -0.064