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ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MLRNTIALRS FIRTQSTRPY PVNVEAVYYA PLKLPIKYGD LVADIQLRSY DNENLDFYSD

70 80 90 100 110 120
FILRTGYYLG IPLTGPKPLP TRRERWTVIK SPFVHAKSKE NFERHTHKRL IRAWDTNPEV

130 140 150 160 170 180
LQMLIAYITK HSMAGVGMKC NFFQRSEISL DLGSDANGLE KSLSNIDELY SLRNDDKAQT

190 200
SAVGQKVLEL LDSPDFKKHL EKK


References and documentation are available.

Number of amino acids: 203 Molecular weight: 23423.90 Theoretical pI: 9.30
Amino acid composition: 
Ala (A) 11 5.4% Arg (R) 14 6.9% Asn (N) 10 4.9% Asp (D) 13 6.4% Cys (C) 1 0.5% Gln (Q) 6 3.0% Glu (E) 11 5.4% Gly (G) 9 4.4% His (H) 5 2.5% Ile (I) 12 5.9% Leu (L) 24 11.8% Lys (K) 16 7.9% Met (M) 4 2.0% Phe (F) 8 3.9% Pro (P) 11 5.4% Ser (S) 15 7.4% Thr (T) 11 5.4% Trp (W) 2 1.0% Tyr (Y) 10 4.9% Val (V) 10 4.9% Pyl (O) 0 0.0% Sec (U) 0 0.0% (B) 0 0.0% (Z) 0 0.0% (X) 0 0.0%
Total number of negatively charged residues (Asp + Glu): 24 Total number of positively charged residues (Arg + Lys): 30 Atomic composition: Carbon C 1055 Hydrogen H 1667 Nitrogen N 289 Oxygen O 304 Sulfur S 5 Formula: C1055H1667N289O304S5 Total number of atoms: 3320 Extinction coefficients: Extinction coefficients are in units of M-1 cm-1, at 280 nm measured in water. Ext. coefficient 25900 Abs 0.1% (=1 g/l) 1.106, assuming all pairs of Cys residues form cystines Ext. coefficient 25900 Abs 0.1% (=1 g/l) 1.106, assuming all Cys residues are reduced Estimated half-life: The N-terminal of the sequence considered is M (Met). The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro). >20 hours (yeast, in vivo). >10 hours (Escherichia coli, in vivo). Instability index: The instability index (II) is computed to be 44.04 This classifies the protein as unstable. Aliphatic index: 88.87 Grand average of hydropathicity (GRAVY): -0.481