ProtParam
User-provided sequence:
10 20 30 40 50 60
MLRQTTKRAF LGLASQNPTP FPVVSRLYHP NVIDHYDNPR NVGSFDKNDP NVGTGLVGAP
70 80 90 100 110 120
QCGDVMKLQV KFDGSGQIID AKFKTFGCGS AIAASSVATE WVKGKSVEEV LTIKNSQIAK
130 140 150 160 170
HLSLPPVKLH CSMLAEDAIK AAIKNYKEKQ DKANGETVET IDSTYLHGIG S
References and
documentation are available.
Number of amino acids: 171
Molecular weight: 18471.08
Theoretical pI: 8.72
Total number of negatively charged residues (Asp + Glu): 17
Total number of positively charged residues (Arg + Lys): 20
Atomic composition:
Carbon C 817
Hydrogen H 1306
Nitrogen N 226
Oxygen O 249
Sulfur S 6
Formula: C
817H
1306N
226O
249S
6
Total number of atoms: 2604
Extinction coefficients:
Extinction coefficients are in units of M
-1 cm
-1, at 280 nm measured in water.
Ext. coefficient 11585
Abs 0.1% (=1 g/l) 0.627, assuming all pairs of Cys residues form cystines
Ext. coefficient 11460
Abs 0.1% (=1 g/l) 0.620, assuming all Cys residues are reduced
Estimated half-life:
The N-terminal of the sequence considered is M (Met).
The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro).
>20 hours (yeast, in vivo).
>10 hours (Escherichia coli, in vivo).
Instability index:
The instability index (II) is computed to be 30.42
This classifies the protein as stable.
Aliphatic index: 82.11
Grand average of hydropathicity (GRAVY): -0.297