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ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MLRQVKPKNA RTKRALEKRE PKLVEGAKTA IFLRGNATSQ ISLDVLGDIH ALKKPFSVNF

70 80 90 100 110 120
QKKNNILPFE DASSLEFFSE KNDAALAVMA THNKKRPHNL TWVRFFNYRV LDMIELGIVN

130 140 150 160 170 180
YKSIQSFSAT PIVPGTKPMI LFQGPVFDAH PTYRHIKSLF LDFFRGEPIQ KLDSAGLSYV

190 200 210 220 230 240
IVVSAAEAQE DETKPLPLVH FRVYGTKLLK TKTNLPRVEL EEMGPRIDFN IRRVQPAESD

250 260 270 280 290 300
VLEEALKKPK TQEPKPKKNV DVDIIGNKVG RIHVDQQDLG NLQTRKMKGL KRSVEEREDS

310
ENEEVEIEED VISDASE


References and documentation are available.

Number of amino acids: 317 Molecular weight: 36071.46 Theoretical pI: 8.96
Amino acid composition: 
Ala (A) 20 6.3% Arg (R) 19 6.0% Asn (N) 16 5.0% Asp (D) 18 5.7% Cys (C) 0 0.0% Gln (Q) 12 3.8% Glu (E) 28 8.8% Gly (G) 14 4.4% His (H) 7 2.2% Ile (I) 19 6.0% Leu (L) 29 9.1% Lys (K) 31 9.8% Met (M) 6 1.9% Phe (F) 16 5.0% Pro (P) 19 6.0% Ser (S) 18 5.7% Thr (T) 14 4.4% Trp (W) 1 0.3% Tyr (Y) 5 1.6% Val (V) 25 7.9% Pyl (O) 0 0.0% Sec (U) 0 0.0% (B) 0 0.0% (Z) 0 0.0% (X) 0 0.0%
Total number of negatively charged residues (Asp + Glu): 46 Total number of positively charged residues (Arg + Lys): 50 Atomic composition: Carbon C 1614 Hydrogen H 2598 Nitrogen N 448 Oxygen O 475 Sulfur S 6 Formula: C1614H2598N448O475S6 Total number of atoms: 5141 Extinction coefficients: Extinction coefficients are in units of M-1 cm-1, at 280 nm measured in water. Ext. coefficient 12950 Abs 0.1% (=1 g/l) 0.359 Estimated half-life: The N-terminal of the sequence considered is M (Met). The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro). >20 hours (yeast, in vivo). >10 hours (Escherichia coli, in vivo). Instability index: The instability index (II) is computed to be 44.26 This classifies the protein as unstable. Aliphatic index: 88.23 Grand average of hydropathicity (GRAVY): -0.513