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ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MLRSSVVRSR ATLRPLLRRA YSSHKELKFG VEGRASLLKG VETLAEAVAA TLGPKGRNVL

70 80 90 100 110 120
IEQPFGPPKI TKDGVTVAKS IVLKDKFENM GAKLLQEVAS KTNEAAGDGT TSATVLGRAI

130 140 150 160 170 180
FTESVKNVAA GCNPMDLRRG SQVAVEKVIE FLSANKKEIT TSEEIAQVAT ISANGDSHVG

190 200 210 220 230 240
KLLASAMEKV GKEGVITIRE GRTLEDELEV TEGMRFDRGF ISPYFITDPK SSKVEFEKPL

250 260 270 280 290 300
LLLSEKKISS IQDILPALEI SNQSRRPLLI IAEDVDGEAL AACILNKLRG QVKVCAVKAP

310 320 330 340 350 360
GFGDNRKNTI GDIAVLTGGT VFTEELDLKP EQCTIENLGS CDSITVTKED TVILNGSGPK

370 380 390 400 410 420
EAIQERIEQI KGSIDITTTN SYEKEKLQER LAKLSGGVAV IRVGGASEVE VGEKKDRYDD

430 440 450 460 470 480
ALNATRAAVE EGILPGGGTA LVKASRVLDE VVVDNFDQKL GVDIIRKAIT RPAKQIIENA

490 500 510 520 530 540
GEEGSVIIGK LIDEYGDDFA KGYDASKSEY TDMLATGIID PFKVVRSGLV DASGVASLLA

550 560 570
TTEVAIVDAP EPPAAAGAGG MPGGMPGMPG MM


References and documentation are available.

Number of amino acids: 572 Molecular weight: 60751.57 Theoretical pI: 5.23
Amino acid composition: 
Ala (A) 56 9.8% Arg (R) 28 4.9% Asn (N) 17 3.0% Asp (D) 32 5.6% Cys (C) 5 0.9% Gln (Q) 13 2.3% Glu (E) 51 8.9% Gly (G) 56 9.8% His (H) 2 0.3% Ile (I) 42 7.3% Leu (L) 49 8.6% Lys (K) 44 7.7% Met (M) 11 1.9% Phe (F) 14 2.4% Pro (P) 23 4.0% Ser (S) 38 6.6% Thr (T) 35 6.1% Trp (W) 0 0.0% Tyr (Y) 7 1.2% Val (V) 49 8.6% Pyl (O) 0 0.0% Sec (U) 0 0.0% (B) 0 0.0% (Z) 0 0.0% (X) 0 0.0%
Total number of negatively charged residues (Asp + Glu): 83 Total number of positively charged residues (Arg + Lys): 72 Atomic composition: Carbon C 2659 Hydrogen H 4402 Nitrogen N 734 Oxygen O 849 Sulfur S 16 Formula: C2659H4402N734O849S16 Total number of atoms: 8660 Extinction coefficients: This protein does not contain any Trp residues. Experience shows that this could result in more than 10% error in the computed extinction coefficient. Extinction coefficients are in units of M-1 cm-1, at 280 nm measured in water. Ext. coefficient 10680 Abs 0.1% (=1 g/l) 0.176, assuming all pairs of Cys residues form cystines Ext. coefficient 10430 Abs 0.1% (=1 g/l) 0.172, assuming all Cys residues are reduced Estimated half-life: The N-terminal of the sequence considered is M (Met). The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro). >20 hours (yeast, in vivo). >10 hours (Escherichia coli, in vivo). Instability index: The instability index (II) is computed to be 39.52 This classifies the protein as stable. Aliphatic index: 96.68 Grand average of hydropathicity (GRAVY): -0.119