ProtParam
User-provided sequence:
10 20 30 40 50 60
MLRTTRLWTT RMPAVSKLFL RNSSGNALNK NKLPFLYSSQ GPQAVRYTSQ HEWIAVHQDK
70 80 90 100 110 120
TAFVGITKYA TDSLGDATYV ELPEVGTEIS QGESLGSIES VKSASEIYQP ADGTVEEINT
130 140 150 160 170
NLEENPGVVN EDPMGDGWLV KMKLGEGVNV EQVEGLMSLE QYEKTLVHDD
References and
documentation are available.
Number of amino acids: 170
Molecular weight: 18794.99
Theoretical pI: 4.66
Total number of negatively charged residues (Asp + Glu): 25
Total number of positively charged residues (Arg + Lys): 14
Atomic composition:
Carbon C 825
Hydrogen H 1298
Nitrogen N 220
Oxygen O 271
Sulfur S 5
Formula: C
825H
1298N
220O
271S
5
Total number of atoms: 2619
Extinction coefficients:
Extinction coefficients are in units of M
-1 cm
-1, at 280 nm measured in water.
Ext. coefficient 25440
Abs 0.1% (=1 g/l) 1.354
Estimated half-life:
The N-terminal of the sequence considered is M (Met).
The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro).
>20 hours (yeast, in vivo).
>10 hours (Escherichia coli, in vivo).
Instability index:
The instability index (II) is computed to be 48.92
This classifies the protein as unstable.
Aliphatic index: 81.35
Grand average of hydropathicity (GRAVY): -0.452