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ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MLSILRNSVR LNSRALRVVP SAANTLTSVQ ASRRLLTSYS SFLQKETKDD KPKSILTDDM

70 80 90 100 110 120
LFKAGVDVDE KGQGKNEETS GEGGEDKNEP SSKSEKSRRK RQTSTDIKRE KYANWFYIFS

130 140 150 160 170 180
LSALTGTAIY MARDWEPQES EELKKDIDNG YTLSLMYKRF KARFNSMFTY FQEPPFPDLL

190 200 210 220 230 240
PPPPPPPYQR PLTLVITLED FLVHSEWSQK HGWRTAKRPG ADYFLGYLSQ YYEIVLFSSN

250 260 270 280 290 300
YMMYSDKIAE KLDPIHAFVS YNLFKEHCVY KDGVHIKDLS KLNRDLSKVI IIDTDPNSYK

310 320 330 340 350 360
LQPENAIPME PWNGEADDKL VRLIPFLEYL ATQQTKDVRP ILNSFEDKKN LAEEFDHRVK

370 380 390 400 410 420
KLKDKFYGDH KSGGNWAMTA LGLGNSLGGS TKFPLDLIHE EGQKNYLMFM KMIEEEKEKI

430 440 450 460 470
RIQQEQMGGQ TFTLKDYVEG NLPSPEEQMK IQLEKQKEVD ALFEEEKKKK KIAESK


References and documentation are available.

Number of amino acids: 476 Molecular weight: 55098.71 Theoretical pI: 6.76
Amino acid composition: 
Ala (A) 22 4.6% Arg (R) 21 4.4% Asn (N) 20 4.2% Asp (D) 31 6.5% Cys (C) 1 0.2% Gln (Q) 20 4.2% Glu (E) 42 8.8% Gly (G) 24 5.0% His (H) 8 1.7% Ile (I) 23 4.8% Leu (L) 47 9.9% Lys (K) 51 10.7% Met (M) 14 2.9% Phe (F) 22 4.6% Pro (P) 26 5.5% Ser (S) 37 7.8% Thr (T) 22 4.6% Trp (W) 6 1.3% Tyr (Y) 21 4.4% Val (V) 18 3.8% Pyl (O) 0 0.0% Sec (U) 0 0.0% (B) 0 0.0% (Z) 0 0.0% (X) 0 0.0%
Total number of negatively charged residues (Asp + Glu): 73 Total number of positively charged residues (Arg + Lys): 72 Atomic composition: Carbon C 2473 Hydrogen H 3864 Nitrogen N 652 Oxygen O 743 Sulfur S 15 Formula: C2473H3864N652O743S15 Total number of atoms: 7747 Extinction coefficients: Extinction coefficients are in units of M-1 cm-1, at 280 nm measured in water. Ext. coefficient 64290 Abs 0.1% (=1 g/l) 1.167, assuming all pairs of Cys residues form cystines Ext. coefficient 64290 Abs 0.1% (=1 g/l) 1.167, assuming all Cys residues are reduced Estimated half-life: The N-terminal of the sequence considered is M (Met). The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro). >20 hours (yeast, in vivo). >10 hours (Escherichia coli, in vivo). Instability index: The instability index (II) is computed to be 45.43 This classifies the protein as unstable. Aliphatic index: 72.94 Grand average of hydropathicity (GRAVY): -0.747