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ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MLSKRIVTAL NTAVKVQNAG IATTARGMAG ASGSEVSKIL EERILGTETG INLEETGKVL

70 80 90 100 110 120
SIGDGIARVY GLKNIQAEEM VEFDSGIKGM AMNLDVDNVG VVVFGNDKVI REGDIVKRTG

130 140 150 160 170 180
AIVDVPVGDG LLGRVVDALG NPIDGKGPIA NARRSRVEVK APGIIPRLSV REPMVTGVKA

190 200 210 220 230 240
VDSLVPIGRG QRELIIGDRQ TGKTAIAIDT IINQKRFNDA GDDKKKLFCI YVAVGQKRST

250 260 270 280 290 300
VAQIVKRLTD AGAMDYTIVV SATASDAAPL QFLAPYSGCA MGEHFRDNGK HALIIFDDLS

310 320 330 340 350 360
KQAVAYRQMS LLLRRPPGRE AYPGDVFYLH SRLLERAAKM NNSLGGGSLT ALPVIETQAG

370 380 390 400 410 420
DVSAYIPTNV ISITDGQIFL ETELFYKGVR PAINVGLSVS RVGSAAQTKA MKQVAGSMKL

430 440 450 460 470 480
ELAQYREVAA FAQFGSDLDA STQQLLNRGV RLTELLKQGQ YVPMGIEEQV GVIYAGVKGY

490 500 510 520 530
LDKVDPSAIT KFEKEFLAHL RSSQQALLKT IREEGQISPQ TDAQLKDVVV NFLATFKP


References and documentation are available.

Number of amino acids: 538 Molecular weight: 57787.58 Theoretical pI: 8.98
Amino acid composition: 
Ala (A) 54 10.0% Arg (R) 32 5.9% Asn (N) 18 3.3% Asp (D) 31 5.8% Cys (C) 2 0.4% Gln (Q) 26 4.8% Glu (E) 28 5.2% Gly (G) 53 9.9% His (H) 4 0.7% Ile (I) 39 7.2% Leu (L) 47 8.7% Lys (K) 33 6.1% Met (M) 13 2.4% Phe (F) 16 3.0% Pro (P) 19 3.5% Ser (S) 30 5.6% Thr (T) 28 5.2% Trp (W) 0 0.0% Tyr (Y) 13 2.4% Val (V) 52 9.7% Pyl (O) 0 0.0% Sec (U) 0 0.0% (B) 0 0.0% (Z) 0 0.0% (X) 0 0.0%
Total number of negatively charged residues (Asp + Glu): 59 Total number of positively charged residues (Arg + Lys): 65 Atomic composition: Carbon C 2553 Hydrogen H 4187 Nitrogen N 719 Oxygen O 772 Sulfur S 15 Formula: C2553H4187N719O772S15 Total number of atoms: 8246 Extinction coefficients: This protein does not contain any Trp residues. Experience shows that this could result in more than 10% error in the computed extinction coefficient. Extinction coefficients are in units of M-1 cm-1, at 280 nm measured in water. Ext. coefficient 19495 Abs 0.1% (=1 g/l) 0.337, assuming all pairs of Cys residues form cystines Ext. coefficient 19370 Abs 0.1% (=1 g/l) 0.335, assuming all Cys residues are reduced Estimated half-life: The N-terminal of the sequence considered is M (Met). The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro). >20 hours (yeast, in vivo). >10 hours (Escherichia coli, in vivo). Instability index: The instability index (II) is computed to be 27.51 This classifies the protein as stable. Aliphatic index: 100.41 Grand average of hydropathicity (GRAVY): -0.026