ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MLSRNLKTLV KNKNILYFTT STSKSNKIYE NAKEAVKDIP NGSKLLVGGF GLCGIPENLI 

        70         80         90        100        110        120 
SAVRDTGVKD LTVVSNNAGV DDFGLGVLLK SRQIKRMISS YVGENATFES QYLKGELEVE 

       130        140        150        160        170        180 
LTPQGNLAER LRAGGAGIPA FYTSTGVGTV LVEEGGFPIK YANDGSGKVE IKSEPRPTQL 

       190        200        210        220        230        240 
YNGRKYCLEE SITGDYALIK AWKADTRGNL VFRNTARNFN PPMATAAKIT IAEVEEIVDA 

       250        260        270        280        290        300 
GEIKPDEVHV PGIYIQRIVK GPSFEKRIER LTVQKEKTGE AAAKPKDEAA AKRERIVRRA 

       310        320        330        340        350        360 
ALEFEDGMYC NLGIGMPTLA SNFIPKGIRI ELQSENGLLG MGPFPKMGEH DADLINAGKE 

       370        380        390        400        410        420 
TVTTIPGSSI FSSADSFAMI RGGHVDLTIL GGMQVSGNGD LANWVIPGSM VKGPGGAMDL 

       430        440        450        460        470        480 
TSSGSRVVVI MEHTTKHGKP KILKNCTLPL TGKSCVNRII TELAVFDVVN GKLELIEVVD 

       490        500 
GQTVDDIKSK TEAEFTVSKN LKPLQQVEI 

References and documentation are available.

Number of amino acids: 509

Molecular weight: 54935.09

Theoretical pI: 8.07

Amino acid composition: 
Ala (A)  36	  7.1%
Arg (R)  22	  4.3%
Asn (N)  27	  5.3%
Asp (D)  22	  4.3%
Cys (C)   5	  1.0%
Gln (Q)  11	  2.2%
Glu (E)  39	  7.7%
Gly (G)  53	 10.4%
His (H)   5	  1.0%
Ile (I)  38	  7.5%
Leu (L)  42	  8.3%
Lys (K)  41	  8.1%
Met (M)  12	  2.4%
Phe (F)  16	  3.1%
Pro (P)  23	  4.5%
Ser (S)  31	  6.1%
Thr (T)  33	  6.5%
Trp (W)   2	  0.4%
Tyr (Y)  11	  2.2%
Val (V)  40	  7.9%
Pyl (O)   0	  0.0%
Sec (U)   0	  0.0%

 (B)   0	  0.0%
 (Z)   0	  0.0%
 (X)   0	  0.0%


Total number of negatively charged residues (Asp + Glu): 61
Total number of positively charged residues (Arg + Lys): 63

Atomic composition:

Carbon      C	      2428
Hydrogen    H	      3948
Nitrogen    N	       666
Oxygen      O	       745
Sulfur      S	        17

Formula: C2428H3948N666O745S17
Total number of atoms: 7804

Extinction coefficients:

Extinction coefficients are in units of  M-1 cm-1, at 280 nm measured in water.

Ext. coefficient    27640
Abs 0.1% (=1 g/l)   0.503, assuming all pairs of Cys residues form cystines


Ext. coefficient    27390
Abs 0.1% (=1 g/l)   0.499, assuming all Cys residues are reduced

Estimated half-life:

The N-terminal of the sequence considered is M (Met).

The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro).
                            >20 hours (yeast, in vivo).
                            >10 hours (Escherichia coli, in vivo).


Instability index:

The instability index (II) is computed to be 25.73
This classifies the protein as stable.



Aliphatic index: 91.16

Grand average of hydropathicity (GRAVY): -0.196