Home  |  Contact

ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MLVCGKGFLK CRAPGVPFFC DKRKSFFTKT KRGFHSLPLG TGVRVYFNNN LRYSSNSIEV

70 80 90 100 110 120
VEKAAINMGS KEDKADNPAL SSYDDAMEAL STLISRRNRG DRTPTKGNRD KLEQVVTYLK

130 140 150 160 170 180
ILDLEDKIKE LKVIHVAGTK GKGSTCVFSE AILRNCGFRT GMFTSPHLID VRERFRIDGL

190 200 210 220 230 240
DISEEKFLQY FWECWKLLKE KAVDGLTMPP LFQFLTVLAF KIFVCEKVDV AVIEVGLGGK

250 260 270 280 290 300
LDSTNVIQKP VVCGIASLGM DHMDILGNTL ADIAFHKAGI FKPQIPAFTV PQLSEAMDVL

310 320 330 340 350 360
QKTANNLEVP LEVVAPLEPK KLDGVTLGLS GDHQLVNAGL AVSLSRCWLQ RTGNWKKIFP

370 380 390 400 410 420
NESKETEIPV AFCRGLATAR LHGRAQVVHD VVSDPQDSSD SMETPCGDLI FYLDGAHSPQ

430 440 450 460 470 480
SMEACGRWFS SAVRGDKSLS TAVNGYMRHG EYGTDLNRVS KQILLFNCME VRDPQVLLPK

490 500 510 520 530 540
LVTTCASSDT HFSRALFVPS MSTYNKVISG ASAIPSDTRR KDLTWQFRLQ RLWEKSIQGT

550 560 570 580 590 600
DAGLDHTLKP DGITALPPHD FLCGDAPQCG GPAGTPVTSS AVMPSLPLTI NWLRDCVRRN

610 620
PSLKLEVLVT GSLHLVGDVL RLLKR


References and documentation are available.

Number of amino acids: 625 Molecular weight: 68977.69 Theoretical pI: 8.69
Amino acid composition: 
Ala (A) 39 6.2% Arg (R) 35 5.6% Asn (N) 22 3.5% Asp (D) 40 6.4% Cys (C) 17 2.7% Gln (Q) 18 2.9% Glu (E) 28 4.5% Gly (G) 47 7.5% His (H) 14 2.2% Ile (I) 27 4.3% Leu (L) 70 11.2% Lys (K) 42 6.7% Met (M) 14 2.2% Phe (F) 29 4.6% Pro (P) 33 5.3% Ser (S) 46 7.4% Thr (T) 37 5.9% Trp (W) 8 1.3% Tyr (Y) 9 1.4% Val (V) 50 8.0% Pyl (O) 0 0.0% Sec (U) 0 0.0% (B) 0 0.0% (Z) 0 0.0% (X) 0 0.0%
Total number of negatively charged residues (Asp + Glu): 68 Total number of positively charged residues (Arg + Lys): 77 Atomic composition: Carbon C 3069 Hydrogen H 4902 Nitrogen N 848 Oxygen O 894 Sulfur S 31 Formula: C3069H4902N848O894S31 Total number of atoms: 9744 Extinction coefficients: Extinction coefficients are in units of M-1 cm-1, at 280 nm measured in water. Ext. coefficient 58410 Abs 0.1% (=1 g/l) 0.847, assuming all pairs of Cys residues form cystines Ext. coefficient 57410 Abs 0.1% (=1 g/l) 0.832, assuming all Cys residues are reduced Estimated half-life: The N-terminal of the sequence considered is M (Met). The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro). >20 hours (yeast, in vivo). >10 hours (Escherichia coli, in vivo). Instability index: The instability index (II) is computed to be 35.60 This classifies the protein as stable. Aliphatic index: 89.97 Grand average of hydropathicity (GRAVY): -0.127