ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MLVTGGHMPR IRLRNDVSSS SFWTRITGQK WSKHHVFIFV HTFMSYAMLH ATRKTLSTVK 

        70         80         90        100        110        120 
PSLIHTWISN TSTPDGPVFP SQQAAAEFLG VLDTGFLVAY AIGLYICGIL GDNYNPRRLL 

       130        140        150        160        170        180 
TAGMMLSSII VFCFGYLTET FHFYSPMVYS FLWILNGFIQ SVGWPVEVSI MGNWFGHNAR 

       190        200        210        220        230        240 
GAVMGAWSSC ASVGNIIGTL IASYTLFLGY QYSFLIACSL LFIYSFLVFF QLPSAPWEVS 

       250        260        270        280        290        300 
SDILPEQMEE EETDDEPTER PPPIGFLKAW LLPGVIAYSL AYACLKLVNY GFFFWLPYYL 

       310        320        330        340        350        360 
HAGLHWPESY ADSLSTWYDV GGIVAAVLAG AFSDHMRSRT PVVFIMLLMA TVSLYIYAHS 

       370        380        390        400        410        420 
PESYNWNAFL LLVAGFFIGG PANMISSSIT ADLGKCDQLR GNAEALSTVT GIIDGTGSIG 

       430        440        450        460        470        480 
AAIGQWFIPS VQHWFGWDAV FYGFIVMILC TALCLVPVLW KEHKERRIHR SEEVDSLLQS 

       490        500 
DSDENLADDI QEIRRRPTNA IV 

References and documentation are available.

Number of amino acids: 502

Molecular weight: 56081.70

Theoretical pI: 5.64

Amino acid composition: 
Ala (A)  39	  7.8%
Arg (R)  18	  3.6%
Asn (N)  15	  3.0%
Asp (D)  19	  3.8%
Cys (C)   8	  1.6%
Gln (Q)  12	  2.4%
Glu (E)  20	  4.0%
Gly (G)  39	  7.8%
His (H)  15	  3.0%
Ile (I)  38	  7.6%
Leu (L)  52	 10.4%
Lys (K)   9	  1.8%
Met (M)  15	  3.0%
Phe (F)  33	  6.6%
Pro (P)  24	  4.8%
Ser (S)  46	  9.2%
Thr (T)  27	  5.4%
Trp (W)  17	  3.4%
Tyr (Y)  22	  4.4%
Val (V)  34	  6.8%
Pyl (O)   0	  0.0%
Sec (U)   0	  0.0%

 (B)   0	  0.0%
 (Z)   0	  0.0%
 (X)   0	  0.0%


Total number of negatively charged residues (Asp + Glu): 39
Total number of positively charged residues (Arg + Lys): 27

Atomic composition:

Carbon      C	      2600
Hydrogen    H	      3887
Nitrogen    N	       639
Oxygen      O	       703
Sulfur      S	        23

Formula: C2600H3887N639O703S23
Total number of atoms: 7852

Extinction coefficients:

Extinction coefficients are in units of  M-1 cm-1, at 280 nm measured in water.

Ext. coefficient   126780
Abs 0.1% (=1 g/l)   2.261, assuming all pairs of Cys residues form cystines


Ext. coefficient   126280
Abs 0.1% (=1 g/l)   2.252, assuming all Cys residues are reduced

Estimated half-life:

The N-terminal of the sequence considered is M (Met).

The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro).
                            >20 hours (yeast, in vivo).
                            >10 hours (Escherichia coli, in vivo).


Instability index:

The instability index (II) is computed to be 47.54
This classifies the protein as unstable.



Aliphatic index: 97.33

Grand average of hydropathicity (GRAVY): 0.346