Home  |  Contact

ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MLVVGMHVEI KRSDGRIHGA VIAEVKSNGR FMVEWYEKGE TKGKESSLEE LLTLNPSLQA

70 80 90 100 110 120
PKPTPPPQPP QKTLQASTAV NRQNGIHAQS MILDDEDTFL LDHINMIPAK GASANKRPTG

130 140 150 160 170 180
AFTQHVPVRM APPSEKPLPT RRAPSPKEDA APAPKSTRTT AAFKPDLDST AITVPKHTAR

190 200 210 220 230 240
RTVVVAPAPA PVPAPPIANM TSQRAPSPVA RVPSPKNVPR SYPQQDVQPS NGNFAFAEMI

250 260 270 280 290 300
RNYRAQIDYR PLSMFDGVNE NRISVCVRKR PLNKKELTKA EVDVITIPSR DITILHQPQT

310 320 330 340 350 360
RVDLTKYLDN QKFRFDYSFD EYANNELVYR FTAAPLVKTV FDNGTATCFA YGQTGSGKTH

370 380 390 400 410 420
TMGGDFSGKK QNASMGIYAL TARDVFRMLE QPQYRRKDLS VHCAFFEIYG TKTYDLLNDK

430 440 450 460 470 480
AELRVLEDKM QKVQVVGLKE EQAHNEQDVL ELINKGTLVR TAGTTSANAN SSRSHAIFQI

490 500 510 520 530 540
ILRQGKKVWG KFSLIDLAGN ERGQDTRECD RDTRKEGANI NTSLLALKEC IRGMARNSSH

550 560 570 580 590 600
VPFRQSKLTM VLRDSFIGEK SRTVMISMIS PGISSSDHTL NTLRYADRVK EMGTDGSGEA

610 620 630 640 650 660
TPIRDEELFL PPSADKSDEE YDEMVEKQEH RRVAVDHVRN LKDMSEKIIR ETTIVLSNEP

670 680
SAAQKAECLA KLDQLAQIVS NTRVAVENV


References and documentation are available.

Number of amino acids: 689 Molecular weight: 76717.22 Theoretical pI: 9.09
Amino acid composition: 
Ala (A) 59 8.6% Arg (R) 49 7.1% Asn (N) 33 4.8% Asp (D) 40 5.8% Cys (C) 6 0.9% Gln (Q) 31 4.5% Glu (E) 44 6.4% Gly (G) 34 4.9% His (H) 15 2.2% Ile (I) 34 4.9% Leu (L) 48 7.0% Lys (K) 46 6.7% Met (M) 20 2.9% Phe (F) 22 3.2% Pro (P) 46 6.7% Ser (S) 48 7.0% Thr (T) 48 7.0% Trp (W) 2 0.3% Tyr (Y) 15 2.2% Val (V) 49 7.1% Pyl (O) 0 0.0% Sec (U) 0 0.0% (B) 0 0.0% (Z) 0 0.0% (X) 0 0.0%
Total number of negatively charged residues (Asp + Glu): 84 Total number of positively charged residues (Arg + Lys): 95 Atomic composition: Carbon C 3348 Hydrogen H 5402 Nitrogen N 978 Oxygen O 1033 Sulfur S 26 Formula: C3348H5402N978O1033S26 Total number of atoms: 10787 Extinction coefficients: Extinction coefficients are in units of M-1 cm-1, at 280 nm measured in water. Ext. coefficient 33725 Abs 0.1% (=1 g/l) 0.440, assuming all pairs of Cys residues form cystines Ext. coefficient 33350 Abs 0.1% (=1 g/l) 0.435, assuming all Cys residues are reduced Estimated half-life: The N-terminal of the sequence considered is M (Met). The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro). >20 hours (yeast, in vivo). >10 hours (Escherichia coli, in vivo). Instability index: The instability index (II) is computed to be 47.96 This classifies the protein as unstable. Aliphatic index: 75.60 Grand average of hydropathicity (GRAVY): -0.558