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ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MLVVQICSSP SHEMFWDISP QGKVPVLKID DKWVTDSDAT VGILEEKYPD PPLKTPAEFA

70 80 90 100 110 120
SVGSNIFEAL ENHLKSHDGP FIAGERVSAV DLSLAPKLYH LQVALGHFKS WSVPESFPHV

130 140 150
HNYMKTLFSL DSFEKTKTEE KCVISGWAPK VNP


References and documentation are available.

Number of amino acids: 153 Molecular weight: 17061.49 Theoretical pI: 5.58
Amino acid composition: 
Ala (A) 9 5.9% Arg (R) 1 0.7% Asn (N) 4 2.6% Asp (D) 9 5.9% Cys (C) 2 1.3% Gln (Q) 3 2.0% Glu (E) 11 7.2% Gly (G) 7 4.6% His (H) 7 4.6% Ile (I) 7 4.6% Leu (L) 13 8.5% Lys (K) 13 8.5% Met (M) 3 2.0% Phe (F) 8 5.2% Pro (P) 13 8.5% Ser (S) 16 10.5% Thr (T) 6 3.9% Trp (W) 4 2.6% Tyr (Y) 3 2.0% Val (V) 14 9.2% Pyl (O) 0 0.0% Sec (U) 0 0.0% (B) 0 0.0% (Z) 0 0.0% (X) 0 0.0%
Total number of negatively charged residues (Asp + Glu): 20 Total number of positively charged residues (Arg + Lys): 14 Atomic composition: Carbon C 780 Hydrogen H 1190 Nitrogen N 194 Oxygen O 226 Sulfur S 5 Formula: C780H1190N194O226S5 Total number of atoms: 2395 Extinction coefficients: Extinction coefficients are in units of M-1 cm-1, at 280 nm measured in water. Ext. coefficient 26595 Abs 0.1% (=1 g/l) 1.559, assuming all pairs of Cys residues form cystines Ext. coefficient 26470 Abs 0.1% (=1 g/l) 1.551, assuming all Cys residues are reduced Estimated half-life: The N-terminal of the sequence considered is M (Met). The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro). >20 hours (yeast, in vivo). >10 hours (Escherichia coli, in vivo). Instability index: The instability index (II) is computed to be 40.76 This classifies the protein as unstable. Aliphatic index: 83.40 Grand average of hydropathicity (GRAVY): -0.204