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ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MMASLKAEET SQMQLVEREE NDEDEDLFEM IDKLIAQGIN AGDVKKLQEA GIHTCNGLMM

70 80 90 100 110 120
HTKKNLTGIK GLSEAKVDKI CEAAEKIVNF GYMTGSDALI KRKSVVKITT GCQALDDLLG

130 140 150 160 170 180
GGIETSAITE AFGEFRSGKT QLAHTLCVTT QLPTNMKGGN GKVAYIDTEG TFRPDRIVPI

190 200 210 220 230 240
AERFGMDPGA VLDNIIYARA YTYEHQYNLL LGLAAKMSEE PFRILIVDSI IALFRVDFTG

250 260 270 280 290 300
RGELADRQQK LAQMLSRLIK IAEEFNVAVY MTNQVIADPG GGMFISDPKK PAGGHVLAHA

310 320 330 340
ATIRLLFRKG KGDTRVCKVY DAPNLAEAEA SFQITQGGIA DAKD


References and documentation are available.

Number of amino acids: 344 Molecular weight: 37513.11 Theoretical pI: 5.53
Amino acid composition: 
Ala (A) 36 10.5% Arg (R) 15 4.4% Asn (N) 12 3.5% Asp (D) 22 6.4% Cys (C) 5 1.5% Gln (Q) 14 4.1% Glu (E) 25 7.3% Gly (G) 32 9.3% His (H) 6 1.7% Ile (I) 27 7.8% Leu (L) 30 8.7% Lys (K) 25 7.3% Met (M) 13 3.8% Phe (F) 13 3.8% Pro (P) 9 2.6% Ser (S) 12 3.5% Thr (T) 22 6.4% Trp (W) 0 0.0% Tyr (Y) 8 2.3% Val (V) 18 5.2% Pyl (O) 0 0.0% Sec (U) 0 0.0% (B) 0 0.0% (Z) 0 0.0% (X) 0 0.0%
Total number of negatively charged residues (Asp + Glu): 47 Total number of positively charged residues (Arg + Lys): 40 Atomic composition: Carbon C 1649 Hydrogen H 2666 Nitrogen N 452 Oxygen O 507 Sulfur S 18 Formula: C1649H2666N452O507S18 Total number of atoms: 5292 Extinction coefficients: This protein does not contain any Trp residues. Experience shows that this could result in more than 10% error in the computed extinction coefficient. Extinction coefficients are in units of M-1 cm-1, at 280 nm measured in water. Ext. coefficient 12170 Abs 0.1% (=1 g/l) 0.324, assuming all pairs of Cys residues form cystines Ext. coefficient 11920 Abs 0.1% (=1 g/l) 0.318, assuming all Cys residues are reduced Estimated half-life: The N-terminal of the sequence considered is M (Met). The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro). >20 hours (yeast, in vivo). >10 hours (Escherichia coli, in vivo). Instability index: The instability index (II) is computed to be 20.58 This classifies the protein as stable. Aliphatic index: 90.26 Grand average of hydropathicity (GRAVY): -0.153