ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MMILGKAGIL AQYGTIYVRQ NTIRNNLSSC IFKQSLCAFH SLAKVLQQKQ VPLDLSYDII 

        70         80         90        100        110        120 
KRDAVKTGDE GKPRPPIIIL HGLFGNKLNN RSIGRNLNKK LGRDVYLLDL RNHGSSPHSS 

       130        140        150        160        170        180 
VHNYEVMSED VKHFITKHEL NTNGGPIIIG HSMGGKVAMM LVLKNPQLCS MLVCIENAPV 

       190        200        210        220        230        240 
SLRPNAEFVE YIKALMEIVN DKGKTIRTLK QADEHLAERI GGNELVRRFL LTALKKVKMD 

       250        260        270        280        290        300 
NSSSVSSYTF EERIPLATLK DAIVKGEIAA WPLDPARERW TRPALFIRAT QSHYVVDEYL 

       310        320        330        340 
PIIGAFFPRF ETRDIDAGHW VNAEKPGECA ESIVDFVERH ED 

References and documentation are available.

Number of amino acids: 342

Molecular weight: 38510.55

Theoretical pI: 8.94

Amino acid composition: 
Ala (A)  23	  6.7%
Arg (R)  21	  6.1%
Asn (N)  19	  5.6%
Asp (D)  17	  5.0%
Cys (C)   5	  1.5%
Gln (Q)   9	  2.6%
Glu (E)  22	  6.4%
Gly (G)  22	  6.4%
His (H)  12	  3.5%
Ile (I)  28	  8.2%
Leu (L)  34	  9.9%
Lys (K)  24	  7.0%
Met (M)   9	  2.6%
Phe (F)  12	  3.5%
Pro (P)  16	  4.7%
Ser (S)  21	  6.1%
Thr (T)  13	  3.8%
Trp (W)   3	  0.9%
Tyr (Y)   9	  2.6%
Val (V)  23	  6.7%
Pyl (O)   0	  0.0%
Sec (U)   0	  0.0%

 (B)   0	  0.0%
 (Z)   0	  0.0%
 (X)   0	  0.0%


Total number of negatively charged residues (Asp + Glu): 39
Total number of positively charged residues (Arg + Lys): 45

Atomic composition:

Carbon      C	      1718
Hydrogen    H	      2754
Nitrogen    N	       484
Oxygen      O	       492
Sulfur      S	        14

Formula: C1718H2754N484O492S14
Total number of atoms: 5462

Extinction coefficients:

Extinction coefficients are in units of  M-1 cm-1, at 280 nm measured in water.

Ext. coefficient    30160
Abs 0.1% (=1 g/l)   0.783, assuming all pairs of Cys residues form cystines


Ext. coefficient    29910
Abs 0.1% (=1 g/l)   0.777, assuming all Cys residues are reduced

Estimated half-life:

The N-terminal of the sequence considered is M (Met).

The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro).
                            >20 hours (yeast, in vivo).
                            >10 hours (Escherichia coli, in vivo).


Instability index:

The instability index (II) is computed to be 38.40
This classifies the protein as stable.



Aliphatic index: 96.93

Grand average of hydropathicity (GRAVY): -0.232