ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MMKESKSITQ HEVERESVSS KRAIKKRLLL FKIDLFVLSF VCLQYWINYV DRVGFTNAYI 

        70         80         90        100        110        120 
SGMKEDLKMV GNDLTVSNTV FMIGYIVGMV PNNLMLLCVP PRIWLSFCTF AWGLLTLGMY 

       130        140        150        160        170        180 
KVTSFKHICA IRFFQALFES CTFSGTHFVL GSWYKEDELP IRSAIFTGSG LVGSMFSGFM 

       190        200        210        220        230        240 
QTSIFTHLNG RNGLAGWRWL FIIDFCITLP IAIYGFIFFP GLPDQTSAVS KFSMTRYIFN 

       250        260        270        280        290        300 
EQELHYARRR LPARDESTRL DWSTIPRVLK RWHWWMFSLV WVLGGENLGF ASNSTFALWL 

       310        320        330        340        350        360 
QNQKYTLAQR NNYPSGIFAV GIVSTLCSAV YMSKIPRARH WHVSVFISLV MVIVAVLIRA 

       370        380        390        400        410        420 
DPLNPKVVFS AQYLGGVAYA GQAVFFSWAN IICHADLQER AIVLASMNMF SGAVNAWWSI 

       430        440        450        460        470        480 
LFFASDMVPK FERGCYALLA TAISSGIVSV VIRSLQIKEN LSKKQVPYID ANDMPGEDDD 

       490        500        510 
DDNQDNENDG DDESMEVELH NEEMAEISNP FR 

References and documentation are available.

Number of amino acids: 512

Molecular weight: 58256.48

Theoretical pI: 6.80

Amino acid composition: 
Ala (A)  35	  6.8%
Arg (R)  25	  4.9%
Asn (N)  25	  4.9%
Asp (D)  23	  4.5%
Cys (C)   9	  1.8%
Gln (Q)  15	  2.9%
Glu (E)  23	  4.5%
Gly (G)  31	  6.1%
His (H)  10	  2.0%
Ile (I)  37	  7.2%
Leu (L)  47	  9.2%
Lys (K)  20	  3.9%
Met (M)  20	  3.9%
Phe (F)  37	  7.2%
Pro (P)  17	  3.3%
Ser (S)  45	  8.8%
Thr (T)  21	  4.1%
Trp (W)  16	  3.1%
Tyr (Y)  16	  3.1%
Val (V)  40	  7.8%
Pyl (O)   0	  0.0%
Sec (U)   0	  0.0%

 (B)   0	  0.0%
 (Z)   0	  0.0%
 (X)   0	  0.0%


Total number of negatively charged residues (Asp + Glu): 46
Total number of positively charged residues (Arg + Lys): 45

Atomic composition:

Carbon      C	      2667
Hydrogen    H	      4063
Nitrogen    N	       683
Oxygen      O	       727
Sulfur      S	        29

Formula: C2667H4063N683O727S29
Total number of atoms: 8169

Extinction coefficients:

Extinction coefficients are in units of  M-1 cm-1, at 280 nm measured in water.

Ext. coefficient   112340
Abs 0.1% (=1 g/l)   1.928, assuming all pairs of Cys residues form cystines


Ext. coefficient   111840
Abs 0.1% (=1 g/l)   1.920, assuming all Cys residues are reduced

Estimated half-life:

The N-terminal of the sequence considered is M (Met).

The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro).
                            >20 hours (yeast, in vivo).
                            >10 hours (Escherichia coli, in vivo).


Instability index:

The instability index (II) is computed to be 37.62
This classifies the protein as stable.



Aliphatic index: 93.48

Grand average of hydropathicity (GRAVY): 0.178