ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MMLRWSGIWG LYPPRIFPSL LVVVALVGLL PVLRSHGLQL NPTASTIRGS EPPRERSIGD 

        70         80         90        100        110        120 
VTTAPSEPLH HPDDRNLTNL YIEHGAKPVR KAFPVLDIDY LHVRTPFEIS LWILLACLMK 

       130        140        150        160        170        180 
IGFHVIPTIS SIVPESCLLI VVGLLVGGLI KGVGETPPFL QSDVFFLFLL PPIILDAGYF 

       190        200        210        220        230        240 
LPLRQFTENL GTILIFAVVG TLWNAFFLGG LLYAVCLVGG EQINNIGLLD TLLFGSIISA 

       250        260        270        280        290        300 
VDPVAVLAVF EEIHINELLH ILVFGESLLN DAVTVVLYHL FEEFASYEYV GISDIFLGFL 

       310        320        330        340        350        360 
SFFVVSLGGV FVGVVYGVIA AFTSRFTSHI RVIEPLFVFL YSYMAYLSAE LFHLSGIMAL 

       370        380        390        400        410        420 
IASGVVMRPY VEANISHKSH TTIKYFLKMW SSVSETLIFI FLGVSTVAGS HQWNWTFVIS 

       430        440        450        460        470        480 
TLLFCLIARV LGVLVLTWFI NKFRIVKLTP KDQFIIAYGG LRGAIAFSLG YLLDKKHFPM 

       490        500        510        520        530        540 
CDLFLTAIIT VIFFTVFVQG MTIRPLVDLL AVKKKQETKR SINEEIHTQF LDHLLTGIED 

       550        560        570        580        590        600 
ICGHYGHHHW KDKLNRFNKK YVKKCLIAGE RSKEPQLIAF YHKMEMKQAI ELVESGGMGK 

       610        620        630        640        650        660 
IPSAVSTVSM QNIHPKSAAS ERILPALSKD KEEEIRKILR SNLQKTRQRL RSYNRHTLVA 

       670        680        690        700        710        720 
DPYEEAWNQM LLRRQKARQL EQKITNYLTV PAHKLDSPTM SRARIGSDPL AYEPKADLPV 

       730        740        750        760        770        780 
ITIDPASPQS PESVDLVNEE LKGKVLGLKR GPRTTPEEEE EDEDGVIMIR SKEPSSPGTD 

       790        800        810        820 
DVFTPGPSDS PGSQRIQRCL SDPGPHPEPG EGEPFIPKGQ 

References and documentation are available.

Number of amino acids: 820

Molecular weight: 91647.07

Theoretical pI: 6.71

Amino acid composition: 
Ala (A)  44	  5.4%
Arg (R)  37	  4.5%
Asn (N)  21	  2.6%
Asp (D)  31	  3.8%
Cys (C)   8	  1.0%
Gln (Q)  22	  2.7%
Glu (E)  50	  6.1%
Gly (G)  58	  7.1%
His (H)  26	  3.2%
Ile (I)  67	  8.2%
Leu (L) 103	 12.6%
Lys (K)  40	  4.9%
Met (M)  16	  2.0%
Phe (F)  47	  5.7%
Pro (P)  52	  6.3%
Ser (S)  58	  7.1%
Thr (T)  41	  5.0%
Trp (W)  10	  1.2%
Tyr (Y)  23	  2.8%
Val (V)  66	  8.0%
Pyl (O)   0	  0.0%
Sec (U)   0	  0.0%

 (B)   0	  0.0%
 (Z)   0	  0.0%
 (X)   0	  0.0%


Total number of negatively charged residues (Asp + Glu): 81
Total number of positively charged residues (Arg + Lys): 77

Atomic composition:

Carbon      C	      4226
Hydrogen    H	      6628
Nitrogen    N	      1076
Oxygen      O	      1148
Sulfur      S	        24

Formula: C4226H6628N1076O1148S24
Total number of atoms: 13102

Extinction coefficients:

Extinction coefficients are in units of  M-1 cm-1, at 280 nm measured in water.

Ext. coefficient    89770
Abs 0.1% (=1 g/l)   0.980, assuming all pairs of Cys residues form cystines


Ext. coefficient    89270
Abs 0.1% (=1 g/l)   0.974, assuming all Cys residues are reduced

Estimated half-life:

The N-terminal of the sequence considered is M (Met).

The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro).
                            >20 hours (yeast, in vivo).
                            >10 hours (Escherichia coli, in vivo).


Instability index:

The instability index (II) is computed to be 52.42
This classifies the protein as unstable.



Aliphatic index: 109.56

Grand average of hydropathicity (GRAVY): 0.209