ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MMNNNGNQVS NLSNALRQVN IGNRNSNTTT DQSNINFEFS TGVNNNNNNN SSSNNNNVQN 

        70         80         90        100        110        120 
NNSGRNGSQN NDNENNIKNT LEQHRQQQQA FSDMSHVEYS RITKFFQEQP LEGYTLFSHR 

       130        140        150        160        170        180 
SAPNGFKVAI VLSELGFHYN TIFLDFNLGE HRAPEFVSVN PNARVPALID HGMDNLSIWE 

       190        200        210        220        230        240 
SGAILLHLVN KYYKETGNPL LWSDDLADQS QINAWLFFQT SGHAPMIGQA LHFRYFHSQK 

       250        260        270        280        290        300 
IASAVERYTD EVRRVYGVVE MALAERREAL VMELDTENAA AYSAGTTPMS QSRFFDYPVW 

       310        320        330        340        350 
LVGDKLTIAD LAFVPWNNVV DRIGINIKIE FPEVYKWTKH MMRRPAVIKA LRGE 

References and documentation are available.

Number of amino acids: 354

Molecular weight: 40270.77

Theoretical pI: 6.00

Amino acid composition: 
Ala (A)  25	  7.1%
Arg (R)  19	  5.4%
Asn (N)  46	 13.0%
Asp (D)  15	  4.2%
Cys (C)   0	  0.0%
Gln (Q)  18	  5.1%
Glu (E)  21	  5.9%
Gly (G)  19	  5.4%
His (H)  11	  3.1%
Ile (I)  18	  5.1%
Leu (L)  26	  7.3%
Lys (K)  11	  3.1%
Met (M)  10	  2.8%
Phe (F)  19	  5.4%
Pro (P)  12	  3.4%
Ser (S)  27	  7.6%
Thr (T)  16	  4.5%
Trp (W)   6	  1.7%
Tyr (Y)  11	  3.1%
Val (V)  24	  6.8%
Pyl (O)   0	  0.0%
Sec (U)   0	  0.0%

 (B)   0	  0.0%
 (Z)   0	  0.0%
 (X)   0	  0.0%


Total number of negatively charged residues (Asp + Glu): 36
Total number of positively charged residues (Arg + Lys): 30

Atomic composition:

Carbon      C	      1773
Hydrogen    H	      2714
Nitrogen    N	       514
Oxygen      O	       545
Sulfur      S	        10

Formula: C1773H2714N514O545S10
Total number of atoms: 5556

Extinction coefficients:

Extinction coefficients are in units of  M-1 cm-1, at 280 nm measured in water.

Ext. coefficient    49390
Abs 0.1% (=1 g/l)   1.226

Estimated half-life:

The N-terminal of the sequence considered is M (Met).

The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro).
                            >20 hours (yeast, in vivo).
                            >10 hours (Escherichia coli, in vivo).


Instability index:

The instability index (II) is computed to be 38.83
This classifies the protein as stable.



Aliphatic index: 75.20

Grand average of hydropathicity (GRAVY): -0.551