ProtParam
User-provided sequence:
10 20 30 40 50 60
MMPAKLQLDV LRTLQSSARH GTQTLKNSNF LERFHKDRIV FCLPFFPALF LVPVQKVLQH
70 80 90 100 110 120
LCLRFTQVAP YFIIQLFDLP SRHAENLAPL LASCRIQYTN CFSSSSNGQV PSIISLYLRV
130 140 150 160
DLSPFYAKKF QIPYRVPMIW LDVFQVFFVF LVISQHSLHS
References and
documentation are available.
Number of amino acids: 160
Molecular weight: 18592.95
Theoretical pI: 9.69
Total number of negatively charged residues (Asp + Glu): 7
Total number of positively charged residues (Arg + Lys): 15
Atomic composition:
Carbon C 868
Hydrogen H 1337
Nitrogen N 223
Oxygen O 217
Sulfur S 7
Formula: C
868H
1337N
223O
217S
7
Total number of atoms: 2652
Extinction coefficients:
Extinction coefficients are in units of M
-1 cm
-1, at 280 nm measured in water.
Ext. coefficient 13200
Abs 0.1% (=1 g/l) 0.710, assuming all pairs of Cys residues form cystines
Ext. coefficient 12950
Abs 0.1% (=1 g/l) 0.697, assuming all Cys residues are reduced
Estimated half-life:
The N-terminal of the sequence considered is M (Met).
The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro).
>20 hours (yeast, in vivo).
>10 hours (Escherichia coli, in vivo).
Instability index:
The instability index (II) is computed to be 53.61
This classifies the protein as unstable.
Aliphatic index: 106.56
Grand average of hydropathicity (GRAVY): 0.306