ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MMPANEDKEN NIVYTGNESS GINFPQTPAH LLKRSHSNIL KPPVRLDQLK RDANSNNGNT 

        70         80         90        100        110        120 
LKYIQGGKEV SPTKRLHTHA QQQGRLPLAA KDNNRSKSFI FPETSNQSKD ADLPQLQNTL 

       130        140        150        160        170        180 
SIRKNDQLRK LSQISRSRSR ANHNDLLSNS RKLQKYGSVL GYNALPKMKS LVLKDLADSG 

       190        200        210        220        230        240 
KNEESSDDDE GNEDSESKLG KKLQSALLKQ DSSDGENELN GGLGLFNEQG GLQQLIKNST 

       250        260        270        280        290        300 
KNEQKTKNDK SDKTDDYDIE IAPQRQEPLP YVPEGYSPFQ QDDIEKLKTF NSPYKLDLED 

       310        320        330        340        350        360 
EDDTPDKVDL LPLEQIDEEG EKDETECITR NQEEGAALPL LSKNFKEVAA VPTMELVYSE 

       370 
EGLDPEELED LVT 

References and documentation are available.

Number of amino acids: 373

Molecular weight: 41838.15

Theoretical pI: 4.86

Amino acid composition: 
Ala (A)  16	  4.3%
Arg (R)  14	  3.8%
Asn (N)  30	  8.0%
Asp (D)  33	  8.8%
Cys (C)   1	  0.3%
Gln (Q)  24	  6.4%
Glu (E)  35	  9.4%
Gly (G)  21	  5.6%
His (H)   5	  1.3%
Ile (I)  13	  3.5%
Leu (L)  45	 12.1%
Lys (K)  35	  9.4%
Met (M)   4	  1.1%
Phe (F)   7	  1.9%
Pro (P)  21	  5.6%
Ser (S)  33	  8.8%
Thr (T)  16	  4.3%
Trp (W)   0	  0.0%
Tyr (Y)   9	  2.4%
Val (V)  11	  2.9%
Pyl (O)   0	  0.0%
Sec (U)   0	  0.0%

 (B)   0	  0.0%
 (Z)   0	  0.0%
 (X)   0	  0.0%


Total number of negatively charged residues (Asp + Glu): 68
Total number of positively charged residues (Arg + Lys): 49

Atomic composition:

Carbon      C	      1799
Hydrogen    H	      2896
Nitrogen    N	       514
Oxygen      O	       622
Sulfur      S	         5

Formula: C1799H2896N514O622S5
Total number of atoms: 5836

Extinction coefficients:

This protein does not contain any Trp residues. Experience shows that
this could result in more than 10% error in the computed extinction coefficient.

Extinction coefficients are in units of  M-1 cm-1, at 280 nm measured in water.

Ext. coefficient    13410
Abs 0.1% (=1 g/l)   0.321, assuming all pairs of Cys residues form cystines


Ext. coefficient    13410
Abs 0.1% (=1 g/l)   0.321, assuming all Cys residues are reduced

Estimated half-life:

The N-terminal of the sequence considered is M (Met).

The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro).
                            >20 hours (yeast, in vivo).
                            >10 hours (Escherichia coli, in vivo).


Instability index:

The instability index (II) is computed to be 59.80
This classifies the protein as unstable.



Aliphatic index: 73.49

Grand average of hydropathicity (GRAVY): -1.071