ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MMSPRLFHQE QSMIDQSTLN TSPQPTITIE DDRTGMSVAT LKRAFLDNLF YLQGIDRSQA 

        70         80         90        100        110        120 
TLYDYYVALA YTIRDRLLHR FIKTVATYKQ EKVKVVCYLS AEFLMGRHLG NNLINLGLYD 

       130        140        150        160        170        180 
KIDQVMKEFD LDLNEIIEQE PDPGLGNGGL GRLAACFLDS LASLEVPAIG YGIRYEFGIF 

       190        200        210        220        230        240 
HQRIQDGWQV EVPDNWLRFG NPWEIPRADE SVEVKLGGHT EIIHNEKNQP KVVWIPERTI 

       250        260        270        280        290        300 
LAIPYDTPVP GYQTNTVNPL RLWKAEASEE FNFEAFNSGL YDRAVAEKMD AETISKVLYP 

       310        320        330        340        350        360 
NDNTPAGREL RLAQQYFFVS ASLQDLIRIH LRTHPNLDTF YELTAIQLND THPAVAIAEL 

       370        380        390        400        410        420 
MRLFVDRYDY DWDKAWDITQ KTFAYTNHTL MPEALERWSV DLFAKLLPRH LEIIYEINHR 

       430        440        450        460        470        480 
FLTGLQTWFP NDEALVESLS LIEENHGKKI RMANLACVGS HAINGVAALH TELLKKDTLR 

       490        500        510        520        530        540 
DFAKLWPQKF FNKTNGVTPR RWILLSNPEL SALVTEKIGD GWLKNLDEMR QIEKFVDDPE 

       550        560        570        580        590        600 
FCRRWREIKQ NNKRNLAAYL LKYRNVQIDV NSLFDVQVKR IHEYKRQHLA ALEIIHLYNR 

       610        620        630        640        650        660 
IKQNPHAEIV PRTFIFGGKA APGYFMAKLI IKLINAVGEV VNNDPDVRGR LKVVFVSNFN 

       670        680        690        700        710        720 
VSLGQRIYPA ADLSEQISTA GKEASGTGNM KFAMNGALTI GTLDGANIEI REEAGPENFF 

       730        740        750        760        770        780 
LFGLTAEQVY AMKENGYHPH TYYDNNFDLK AVIDRIAHGY FSPGNPNLFH PIVESLLHHD 

       790        800        810        820        830        840 
PYMLLADYQA YVGCQDEVSK AYADQDRWTK MSILNSARMG KFSSDRTIRE YCKEIWDVPP 

       850 
VKISLDEYHP EYADL 

References and documentation are available.

Number of amino acids: 855

Molecular weight: 98304.99

Theoretical pI: 5.76

Amino acid composition: 
Ala (A)  65	  7.6%
Arg (R)  48	  5.6%
Asn (N)  51	  6.0%
Asp (D)  54	  6.3%
Cys (C)   6	  0.7%
Gln (Q)  33	  3.9%
Glu (E)  59	  6.9%
Gly (G)  46	  5.4%
His (H)  26	  3.0%
Ile (I)  58	  6.8%
Leu (L)  89	 10.4%
Lys (K)  45	  5.3%
Met (M)  18	  2.1%
Phe (F)  40	  4.7%
Pro (P)  40	  4.7%
Ser (S)  35	  4.1%
Thr (T)  41	  4.8%
Trp (W)  15	  1.8%
Tyr (Y)  38	  4.4%
Val (V)  48	  5.6%
Pyl (O)   0	  0.0%
Sec (U)   0	  0.0%

 (B)   0	  0.0%
 (Z)   0	  0.0%
 (X)   0	  0.0%


Total number of negatively charged residues (Asp + Glu): 113
Total number of positively charged residues (Arg + Lys): 93

Atomic composition:

Carbon      C	      4447
Hydrogen    H	      6851
Nitrogen    N	      1195
Oxygen      O	      1280
Sulfur      S	        24

Formula: C4447H6851N1195O1280S24
Total number of atoms: 13797

Extinction coefficients:

Extinction coefficients are in units of  M-1 cm-1, at 280 nm measured in water.

Ext. coefficient   139495
Abs 0.1% (=1 g/l)   1.419, assuming all pairs of Cys residues form cystines


Ext. coefficient   139120
Abs 0.1% (=1 g/l)   1.415, assuming all Cys residues are reduced

Estimated half-life:

The N-terminal of the sequence considered is M (Met).

The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro).
                            >20 hours (yeast, in vivo).
                            >10 hours (Escherichia coli, in vivo).


Instability index:

The instability index (II) is computed to be 38.80
This classifies the protein as stable.



Aliphatic index: 90.94

Grand average of hydropathicity (GRAVY): -0.336