ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MMSSSSIRMS SGGSSRLSVG GGAGRVSGVR AGSVYGGAGG SGVRISSSSA SRSFSAGGGA 

        70         80         90        100        110        120 
GFGGGAGAGF NLSDAIDVST NEKATMQNLN DRLASYLEKV RSLEKANADL ELKIRQFLDS 

       130        140        150        160        170        180 
KATPNARDYS AYYATISDLQ AKILHATGVN GGIYLSIDNA KLAADDFRVK YENELTMRQS 

       190        200        210        220        230        240 
VEADIVGLRK VLDELTMTRS DLELQIEGLK EELIFLKKNH EEELLAARTQ MSGQVNVEVD 

       250        260        270        280        290        300 
AAPQEDLTKI MADIREHYEA VSAKNRKDLE SWFQAKSESL NKEVAVSTET LQTSRSEITE 

       310        320        330        340        350        360 
VKRTLQSLEI ELQSQLSMKA SLEGTLADTQ ARYTNMLNGY QFQVSSLEEQ LIQLRADLER 

       370        380        390        400        410        420 
QGQEYQMLLD IKTRLEMEIA EYRRLLDGEA TSVSTSSSTT RKVVTIVEEV VDGKVVSSSS 


KATTETKTT 

References and documentation are available.

Number of amino acids: 429

Molecular weight: 46646.19

Theoretical pI: 5.13

Amino acid composition: 
Ala (A)  39	  9.1%
Arg (R)  26	  6.1%
Asn (N)  15	  3.5%
Asp (D)  22	  5.1%
Cys (C)   0	  0.0%
Gln (Q)  21	  4.9%
Glu (E)  39	  9.1%
Gly (G)  33	  7.7%
His (H)   3	  0.7%
Ile (I)  19	  4.4%
Leu (L)  44	 10.3%
Lys (K)  24	  5.6%
Met (M)  12	  2.8%
Phe (F)   8	  1.9%
Pro (P)   2	  0.5%
Ser (S)  52	 12.1%
Thr (T)  29	  6.8%
Trp (W)   1	  0.2%
Tyr (Y)  12	  2.8%
Val (V)  28	  6.5%
Pyl (O)   0	  0.0%
Sec (U)   0	  0.0%

 (B)   0	  0.0%
 (Z)   0	  0.0%
 (X)   0	  0.0%


Total number of negatively charged residues (Asp + Glu): 61
Total number of positively charged residues (Arg + Lys): 50

Atomic composition:

Carbon      C	      2000
Hydrogen    H	      3278
Nitrogen    N	       574
Oxygen      O	       681
Sulfur      S	        12

Formula: C2000H3278N574O681S12
Total number of atoms: 6545

Extinction coefficients:

Extinction coefficients are in units of  M-1 cm-1, at 280 nm measured in water.

Ext. coefficient    23380
Abs 0.1% (=1 g/l)   0.501

Estimated half-life:

The N-terminal of the sequence considered is M (Met).

The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro).
                            >20 hours (yeast, in vivo).
                            >10 hours (Escherichia coli, in vivo).


Instability index:

The instability index (II) is computed to be 43.09
This classifies the protein as unstable.



Aliphatic index: 85.29

Grand average of hydropathicity (GRAVY): -0.393