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ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MMTNSDSDHC TPAKTSISGD GLEKESDFKK QLNSEIDPQA SSSQNDAITM EDGAVSVNNR

70 80 90 100 110 120
DLQEIKESSF SKGSEQYRVD GALEESLNFE EKEQESEAQR LLEAEKRRLL AEIELGSIFR

130 140 150 160 170 180
KSVDVDTLPK IEETMDNDVD KIELVDHTAL VDVVHHPKRP GTAQNEKDTP RKLKKIGDKR

190 200 210 220 230 240
NVIEGSGVEN NGKQFRRLYT RKQLESMRFA HIVNQKNLWS EMYSRILPEV VTEYESLVYV

250 260 270 280 290 300
KNYKSSKSNR VRGRTESGNE ENLGTEEGTE DPEDYTDDND DYNSILRPAF EVDGEPDFST

310 320 330 340 350 360
GPPEDGLEYL RRVRWEAKGI PNVRVAKIDE STYIKKEQSV YMPLIPEIPK CPEYLLPMKE

370 380 390 400 410 420
WEDSLLLDFV HLRQTLTQSA NSCEDEIISS QCVEDLLVEM FNKHLHTEED ESFGEVVTDI

430 440 450 460 470 480
QGMDSVTRVS KLKKRICLVE KESGLQSSDC KWVVALCASL ETPLDADTCA CLRGLLRKCA

490 500 510
SVRAETSLEV GDEEVITMAN MLITIAGRYF GQMGQ


References and documentation are available.

Number of amino acids: 515 Molecular weight: 58339.21 Theoretical pI: 4.72
Amino acid composition: 
Ala (A) 23 4.5% Arg (R) 29 5.6% Asn (N) 23 4.5% Asp (D) 39 7.6% Cys (C) 10 1.9% Gln (Q) 19 3.7% Glu (E) 62 12.0% Gly (G) 27 5.2% His (H) 8 1.6% Ile (I) 25 4.9% Leu (L) 45 8.7% Lys (K) 36 7.0% Met (M) 13 2.5% Phe (F) 12 2.3% Pro (P) 19 3.7% Ser (S) 45 8.7% Thr (T) 27 5.2% Trp (W) 4 0.8% Tyr (Y) 13 2.5% Val (V) 36 7.0% Pyl (O) 0 0.0% Sec (U) 0 0.0% (B) 0 0.0% (Z) 0 0.0% (X) 0 0.0%
Total number of negatively charged residues (Asp + Glu): 101 Total number of positively charged residues (Arg + Lys): 65 Atomic composition: Carbon C 2516 Hydrogen H 4026 Nitrogen N 700 Oxygen O 845 Sulfur S 23 Formula: C2516H4026N700O845S23 Total number of atoms: 8110 Extinction coefficients: Extinction coefficients are in units of M-1 cm-1, at 280 nm measured in water. Ext. coefficient 41995 Abs 0.1% (=1 g/l) 0.720, assuming all pairs of Cys residues form cystines Ext. coefficient 41370 Abs 0.1% (=1 g/l) 0.709, assuming all Cys residues are reduced Estimated half-life: The N-terminal of the sequence considered is M (Met). The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro). >20 hours (yeast, in vivo). >10 hours (Escherichia coli, in vivo). Instability index: The instability index (II) is computed to be 50.47 This classifies the protein as unstable. Aliphatic index: 77.75 Grand average of hydropathicity (GRAVY): -0.688