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ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MNCKNMDTSY EIINYLTKDE LDIDLSCMDK KERYKIWKRL PKCELHCHLD VCFSVDFFLN

70 80 90 100 110 120
VIRKYNIQPN MSDEEIIDYY LFSKPGKSLD EFVEKALRLT DIYIDYTVVE DLAKHAVFNK

130 140 150 160 170 180
YKEGVVLMEF RYSPSFMSFK HNLDKDLIHE AIVKGLNEAV ALLEYKIQVG LLCTGDGGLS

190 200 210 220 230 240
HERMKEAAEF CIKHKKDFVG YDHAGHEVDL KPFKDIFDNI REEGISLSVH AGEDVSIPNL

250 260 270 280 290 300
NSLYTAINLL HVKRIGHGIR VSESQELIDL VKEKDILLEV CPISNVLLNN VKSMDTHPIR

310 320 330 340 350 360
MLYDAGVKVS VNSDDPGMFL TNITDNYEEL YTHLNFTLAD FMKMNLWAVQ KSFVDPDIKN


KIISKYF


References and documentation are available.

Number of amino acids: 367 Molecular weight: 42465.91 Theoretical pI: 5.41
Amino acid composition: 
Ala (A) 14 3.8% Arg (R) 10 2.7% Asn (N) 22 6.0% Asp (D) 32 8.7% Cys (C) 8 2.2% Gln (Q) 4 1.1% Glu (E) 27 7.4% Gly (G) 15 4.1% His (H) 14 3.8% Ile (I) 29 7.9% Leu (L) 39 10.6% Lys (K) 34 9.3% Met (M) 12 3.3% Phe (F) 18 4.9% Pro (P) 10 2.7% Ser (S) 22 6.0% Thr (T) 11 3.0% Trp (W) 2 0.5% Tyr (Y) 17 4.6% Val (V) 27 7.4% Pyl (O) 0 0.0% Sec (U) 0 0.0% (B) 0 0.0% (Z) 0 0.0% (X) 0 0.0%
Total number of negatively charged residues (Asp + Glu): 59 Total number of positively charged residues (Arg + Lys): 44 Atomic composition: Carbon C 1915 Hydrogen H 2987 Nitrogen N 487 Oxygen O 562 Sulfur S 20 Formula: C1915H2987N487O562S20 Total number of atoms: 5971 Extinction coefficients: Extinction coefficients are in units of M-1 cm-1, at 280 nm measured in water. Ext. coefficient 36830 Abs 0.1% (=1 g/l) 0.867, assuming all pairs of Cys residues form cystines Ext. coefficient 36330 Abs 0.1% (=1 g/l) 0.856, assuming all Cys residues are reduced Estimated half-life: The N-terminal of the sequence considered is M (Met). The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro). >20 hours (yeast, in vivo). >10 hours (Escherichia coli, in vivo). Instability index: The instability index (II) is computed to be 27.21 This classifies the protein as stable. Aliphatic index: 97.41 Grand average of hydropathicity (GRAVY): -0.220