ProtParam
User-provided sequence:
10 20 30 40 50 60
MNDPSLLGYP NVGPQQQQQQ QQQQHAGLLG KGTPNALQQQ LHMNQLTGIP PPGLMNNSDV
70 80 90 100 110 120
HTSSNNNSRQ LLDQLANGNA NMLNMNMDNN NNNNNNNNNN NNNGGGSGVM MNASTAAVNS
130 140 150 160 170 180
IGMVPTVGTP VNINVNASNP LLHPHLDDPS LLNNPIWKLQ LHLAAVSAQS LGQPNIYARQ
190 200 210 220 230 240
NAMKKYLATQ QAQQAQQQAQ QQAQQQVPGP FGPGPQAAPP ALQPTDFQQS HIAEASKSLV
250 260 270 280 290 300
DCTKQALMEM ADTLTDSKTA KKQQPTGDST PSGTATNSAV STPLTPKIEL FANGKDEANQ
310 320 330 340 350 360
ALLQHKKLSQ YSIDEDDDIE NRMVMPKDSK YDDQLWHALD LSNLQIFNIS ANIFKYDFLT
370 380 390 400 410 420
RLYLNGNSLT ELPAEIKNLS NLRVLDLSHN RLTSLPAELG SCFQLKYFYF FDNMVTTLPW
430 440 450 460 470 480
EFGNLCNLQF LGVEGNPLEK QFLKILTEKS VTGLIFYLRD NRPEIPLPHE RRFIEINTDG
490 500 510 520 530 540
EPQREYDSLQ QSTEHLATDL AKRTFTVLSY NTLCQHYATP KMYRYTPSWA LSWDYRRNKL
550 560 570 580 590 600
KEQILSYDSD LLCLQEVESK TFEEYWVPLL DKHGYTGIFH AKARAKTMHS KDSKKVDGCC
610 620 630 640 650 660
IFFKRDQFKL ITKDAMDFSG AWMKHKKFQR TEDYLNRAMN KDNVALFLKL QHIPSGDTIW
670 680 690 700 710 720
AVTTHLHWDP KFNDVKTFQV GVLLDHLETL LKEETSHNFR QDIKKFPVLI CGDFNSYINS
730 740 750 760 770 780
AVYELINTGR VQIHQEGNGR DFGYMSEKNF SHNLALKSSY NCIGELPFTN FTPSFTDVID
790 800 810 820 830
YIWFSTHALR VRGLLGEVDP EYVSKFIGFP NDKFPSDHIP LLARFEFMKT NTGSKKV
References and
documentation are available.
Number of amino acids: 837
Molecular weight: 94669.73
Theoretical pI: 6.37
Total number of negatively charged residues (Asp + Glu): 85
Total number of positively charged residues (Arg + Lys): 77
Atomic composition:
Carbon C 4201
Hydrogen H 6505
Nitrogen N 1161
Oxygen O 1275
Sulfur S 31
Formula: C
4201H
6505N
1161O
1275S
31
Total number of atoms: 13173
Extinction coefficients:
Extinction coefficients are in units of M
-1 cm
-1, at 280 nm measured in water.
Ext. coefficient 94240
Abs 0.1% (=1 g/l) 0.995, assuming all pairs of Cys residues form cystines
Ext. coefficient 93740
Abs 0.1% (=1 g/l) 0.990, assuming all Cys residues are reduced
Estimated half-life:
The N-terminal of the sequence considered is M (Met).
The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro).
>20 hours (yeast, in vivo).
>10 hours (Escherichia coli, in vivo).
Instability index:
The instability index (II) is computed to be 44.20
This classifies the protein as unstable.
Aliphatic index: 76.58
Grand average of hydropathicity (GRAVY): -0.560