ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MNDTLSSFLN RNEALGLNPP HGLDMHITKR GSDWLWAVFA VFGFILLCYV VMFFIAENKG 

        70         80         90        100        110        120 
SRLTRYALAP AFLITFFEFF AFFTYASDLG WTGVQAEFNH VKVSKSITGE VPGIRQIFYS 

       130        140        150        160        170        180 
KYIAWFLSWP CLLFLIELAA STTGENDDIS ALDMVHSLLI QIVGTLFWVV SLLVGSLIKS 

       190        200        210        220        230        240 
TYKWGYYTIG AVAMLVTQGV ICQRQFFNLK TRGFNALMLC TCMVIVWLYF ICWGLSDGGN 

       250        260        270        280        290        300 
RIQPDGEAIF YGVLDLCVFA IYPCYLLIAV SRDGKLPRLS LTGGFSHHHA TDDVEDAAPE 

       310        320        330 
TKEAVPESPR ASGETAIHEP EPEAEQAVED TA 

References and documentation are available.

Number of amino acids: 332

Molecular weight: 37044.77

Theoretical pI: 5.06

Amino acid composition: 
Ala (A)  29	  8.7%
Arg (R)  11	  3.3%
Asn (N)  10	  3.0%
Asp (D)  15	  4.5%
Cys (C)   8	  2.4%
Gln (Q)   8	  2.4%
Glu (E)  18	  5.4%
Gly (G)  25	  7.5%
His (H)   8	  2.4%
Ile (I)  22	  6.6%
Leu (L)  37	 11.1%
Lys (K)  10	  3.0%
Met (M)   7	  2.1%
Phe (F)  25	  7.5%
Pro (P)  13	  3.9%
Ser (S)  21	  6.3%
Thr (T)  20	  6.0%
Trp (W)   9	  2.7%
Tyr (Y)  12	  3.6%
Val (V)  24	  7.2%
Pyl (O)   0	  0.0%
Sec (U)   0	  0.0%

 (B)   0	  0.0%
 (Z)   0	  0.0%
 (X)   0	  0.0%


Total number of negatively charged residues (Asp + Glu): 33
Total number of positively charged residues (Arg + Lys): 21

Atomic composition:

Carbon      C	      1714
Hydrogen    H	      2582
Nitrogen    N	       418
Oxygen      O	       470
Sulfur      S	        15

Formula: C1714H2582N418O470S15
Total number of atoms: 5199

Extinction coefficients:

Extinction coefficients are in units of  M-1 cm-1, at 280 nm measured in water.

Ext. coefficient    67880
Abs 0.1% (=1 g/l)   1.832, assuming all pairs of Cys residues form cystines


Ext. coefficient    67380
Abs 0.1% (=1 g/l)   1.819, assuming all Cys residues are reduced

Estimated half-life:

The N-terminal of the sequence considered is M (Met).

The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro).
                            >20 hours (yeast, in vivo).
                            >10 hours (Escherichia coli, in vivo).


Instability index:

The instability index (II) is computed to be 29.64
This classifies the protein as stable.



Aliphatic index: 99.01

Grand average of hydropathicity (GRAVY): 0.355