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ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MNDVAIVKEG WLHKRGEYIK TWRPRYFLLK NDGTFIGYKE RPQDVEQRES PLNNFSVAQC

70 80 90 100 110 120
QLMKTERPRP NTFIIRCLQW TTVIERTFHV ETPEEREEWT TAIQTVADGL KRQEEETMDF

130 140 150 160 170 180
RSGSPSDNSG AEEMEVALAK PKHRVTMNEF EYLKLLGKGT FGKVILVKEK ATGRYYAMKI

190 200 210 220 230 240
LKKEVIVAKD EVAHTLTENR VLQNSRHPFL TALKYSFQTH DRLCFVMEYA NGGELFFHLS

250 260 270 280 290 300
RERVFSEDRA RFYGAEIVSA LDYLHSEKNV VYRDLKLENL MLDKDGHIKI TDFGLCKEGI

310 320 330 340 350 360
KDGATMKTFC GTPEYLAPEV LEDNDYGRAV DWWGLGVVMY EMMCGRLPFY NQDHEKLFEL

370 380 390 400 410 420
ILMEEIRFPR TLGPEAKSLL SGLLKKDPTQ RLGGGSEDAK EIMQHRFFAN IVWQDVYEKK

430 440 450 460 470 480
LSPPFKPQVT SETDTRYFDE EFTAQMITIT PPDQDDSMEC VDSERRPHFP QFSYSASGTA


References and documentation are available.

Number of amino acids: 480 Molecular weight: 55735.40 Theoretical pI: 5.63
Amino acid composition: 
Ala (A) 25 5.2% Arg (R) 31 6.5% Asn (N) 15 3.1% Asp (D) 28 5.8% Cys (C) 7 1.5% Gln (Q) 17 3.5% Glu (E) 49 10.2% Gly (G) 29 6.0% His (H) 12 2.5% Ile (I) 20 4.2% Leu (L) 41 8.5% Lys (K) 34 7.1% Met (M) 16 3.3% Phe (F) 27 5.6% Pro (P) 22 4.6% Ser (S) 22 4.6% Thr (T) 32 6.7% Trp (W) 7 1.5% Tyr (Y) 18 3.8% Val (V) 28 5.8% Pyl (O) 0 0.0% Sec (U) 0 0.0% (B) 0 0.0% (Z) 0 0.0% (X) 0 0.0%
Total number of negatively charged residues (Asp + Glu): 77 Total number of positively charged residues (Arg + Lys): 65 Atomic composition: Carbon C 2490 Hydrogen H 3852 Nitrogen N 670 Oxygen O 739 Sulfur S 23 Formula: C2490H3852N670O739S23 Total number of atoms: 7774 Extinction coefficients: Extinction coefficients are in units of M-1 cm-1, at 280 nm measured in water. Ext. coefficient 65695 Abs 0.1% (=1 g/l) 1.179, assuming all pairs of Cys residues form cystines Ext. coefficient 65320 Abs 0.1% (=1 g/l) 1.172, assuming all Cys residues are reduced Estimated half-life: The N-terminal of the sequence considered is M (Met). The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro). >20 hours (yeast, in vivo). >10 hours (Escherichia coli, in vivo). Instability index: The instability index (II) is computed to be 36.93 This classifies the protein as stable. Aliphatic index: 71.69 Grand average of hydropathicity (GRAVY): -0.576