ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MNFPTIPHES NVVSINVGGR IFQTTKQTLS LAGTDSLLSQ LATETTRFVD RDPDLFSVLL 

        70         80         90        100        110        120 
YILRTGNLPA RSRAFDVRDL IDESRYYGIE SFLIDSLSNS SQFEPFDLRR SRILQLNGRD 

       130        140        150        160        170        180 
SPSSISPTVI GGGLHVAHGS KITSFDWSLR QKSTVLTNFS AVDSLLEISP GVLAAGATDF 

       190        200        210        220        230        240 
PGLQIIDLDN GGFVRTTLNW ENVTRSSSTV QAIGSSHEFL FTSFESSRRN SNSIMVYDLS 

       250        260        270        280        290        300 
SLLPVSEIDH CEIYGADIDS AIPSTKLKWI QSCNLLMVSG SHTSPSGVNG HIRFWDVRSR 

       310        320        330        340        350        360 
NMVWEIKEAQ DCFSDVTVSD NLSAVFKVGV TSGEVFYADL RSLGTKDPWV CLGEEKKRNL 

       370        380        390        400        410        420 
NERRGVGSKI ESYGNHVFCS SKGSGIELWS EVITGLVGNA SRDVLEERVF RKNSLGKLAD 

       430        440        450 
SGENKITGLA FGGNRMFVTR KDQQSVQVWQ SPSRGISI 

References and documentation are available.

Number of amino acids: 458

Molecular weight: 50419.63

Theoretical pI: 5.96

Amino acid composition: 
Ala (A)  18	  3.9%
Arg (R)  30	  6.6%
Asn (N)  23	  5.0%
Asp (D)  28	  6.1%
Cys (C)   5	  1.1%
Gln (Q)  14	  3.1%
Glu (E)  23	  5.0%
Gly (G)  37	  8.1%
His (H)   8	  1.7%
Ile (I)  29	  6.3%
Leu (L)  43	  9.4%
Lys (K)  16	  3.5%
Met (M)   5	  1.1%
Phe (F)  23	  5.0%
Pro (P)  14	  3.1%
Ser (S)  64	 14.0%
Thr (T)  27	  5.9%
Trp (W)   8	  1.7%
Tyr (Y)   7	  1.5%
Val (V)  36	  7.9%
Pyl (O)   0	  0.0%
Sec (U)   0	  0.0%

 (B)   0	  0.0%
 (Z)   0	  0.0%
 (X)   0	  0.0%


Total number of negatively charged residues (Asp + Glu): 51
Total number of positively charged residues (Arg + Lys): 46

Atomic composition:

Carbon      C	      2221
Hydrogen    H	      3505
Nitrogen    N	       625
Oxygen      O	       696
Sulfur      S	        10

Formula: C2221H3505N625O696S10
Total number of atoms: 7057

Extinction coefficients:

Extinction coefficients are in units of  M-1 cm-1, at 280 nm measured in water.

Ext. coefficient    54680
Abs 0.1% (=1 g/l)   1.084, assuming all pairs of Cys residues form cystines


Ext. coefficient    54430
Abs 0.1% (=1 g/l)   1.080, assuming all Cys residues are reduced

Estimated half-life:

The N-terminal of the sequence considered is M (Met).

The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro).
                            >20 hours (yeast, in vivo).
                            >10 hours (Escherichia coli, in vivo).


Instability index:

The instability index (II) is computed to be 51.62
This classifies the protein as unstable.



Aliphatic index: 88.03

Grand average of hydropathicity (GRAVY): -0.198