ProtParam
User-provided sequence:
10 20 30 40 50 60
MNGGGKNVLN KNSVGSVSEV GPDSTQEETP RDVRLLHLLL ASQSIHQYED QVPLQLMDFA
70 80 90 100 110 120
HRYTQGVLKD ALVYNDYAGS GNSAGSGLGV EDIRLAIAAR TQYQFKPTAP KELMLQLAAE
130 140 150
RNKKALPQVM GTWGVRLPPE KYCLTAKEWD LEDPKSM
References and
documentation are available.
Number of amino acids: 157
Molecular weight: 17314.65
Theoretical pI: 5.91
Total number of negatively charged residues (Asp + Glu): 19
Total number of positively charged residues (Arg + Lys): 17
Atomic composition:
Carbon C 761
Hydrogen H 1213
Nitrogen N 213
Oxygen O 236
Sulfur S 6
Formula: C
761H
1213N
213O
236S
6
Total number of atoms: 2429
Extinction coefficients:
Extinction coefficients are in units of M
-1 cm
-1, at 280 nm measured in water.
Ext. coefficient 19940
Abs 0.1% (=1 g/l) 1.152, assuming all pairs of Cys residues form cystines
Ext. coefficient 19940
Abs 0.1% (=1 g/l) 1.152, assuming all Cys residues are reduced
Estimated half-life:
The N-terminal of the sequence considered is M (Met).
The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro).
>20 hours (yeast, in vivo).
>10 hours (Escherichia coli, in vivo).
Instability index:
The instability index (II) is computed to be 28.89
This classifies the protein as stable.
Aliphatic index: 83.25
Grand average of hydropathicity (GRAVY): -0.480