ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MNILNKLGIG SSRQTNMDPS PIAQVIDDEA PAPGNQFTQF GAGCFWSVEL AYQRVPGVTQ 

        70         80         90        100        110        120 
TEVGYSQGIT HDPSYKDVCS GTTNHAEIVR VQYDPKECSY QSLLDLFWSK HDPTTLNRQG 

       130        140        150        160        170        180 
NDVGTQYRSG IYFYNPEQEK LARESLERHQ QQVDRKVVTE ILPAKKFYRA EEHHQQYLSK 

       190        200 
GGRFGLKQST EKGCNDPIRC YG 

References and documentation are available.

Number of amino acids: 202

Molecular weight: 22898.45

Theoretical pI: 6.30

Amino acid composition: 
Ala (A)   9	  4.5%
Arg (R)  11	  5.4%
Asn (N)   9	  4.5%
Asp (D)  11	  5.4%
Cys (C)   5	  2.5%
Gln (Q)  18	  8.9%
Glu (E)  13	  6.4%
Gly (G)  17	  8.4%
His (H)   6	  3.0%
Ile (I)   9	  4.5%
Leu (L)  12	  5.9%
Lys (K)  11	  5.4%
Met (M)   2	  1.0%
Phe (F)   7	  3.5%
Pro (P)  11	  5.4%
Ser (S)  14	  6.9%
Thr (T)  12	  5.9%
Trp (W)   2	  1.0%
Tyr (Y)  11	  5.4%
Val (V)  12	  5.9%
Pyl (O)   0	  0.0%
Sec (U)   0	  0.0%

 (B)   0	  0.0%
 (Z)   0	  0.0%
 (X)   0	  0.0%


Total number of negatively charged residues (Asp + Glu): 24
Total number of positively charged residues (Arg + Lys): 22

Atomic composition:

Carbon      C	      1004
Hydrogen    H	      1543
Nitrogen    N	       287
Oxygen      O	       315
Sulfur      S	         7

Formula: C1004H1543N287O315S7
Total number of atoms: 3156

Extinction coefficients:

Extinction coefficients are in units of  M-1 cm-1, at 280 nm measured in water.

Ext. coefficient    27640
Abs 0.1% (=1 g/l)   1.207, assuming all pairs of Cys residues form cystines


Ext. coefficient    27390
Abs 0.1% (=1 g/l)   1.196, assuming all Cys residues are reduced

Estimated half-life:

The N-terminal of the sequence considered is M (Met).

The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro).
                            >20 hours (yeast, in vivo).
                            >10 hours (Escherichia coli, in vivo).


Instability index:

The instability index (II) is computed to be 40.85
This classifies the protein as unstable.



Aliphatic index: 62.23

Grand average of hydropathicity (GRAVY): -0.800