ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MNIQSNNSPN LSNNIVSKQV YYAHPPPTID PNDPVQISFP TTEVVGHGSF GVVFATVIQE 

        70         80         90        100        110        120 
TNEKVAIKKV LQDKRFKNRE LEIMKMLSHI NIIDLKYFFY ERDSQDEIYL NLILEYMPQS 

       130        140        150        160        170        180 
LYQRLRHFVH QRTPMSRLEI KYYMFQLFKS LNYLHHFANV CHRDIKPQNL LVDPETWSLK 

       190        200        210        220        230        240 
LCDFGSAKQL KPTEPNVSYI CSRYYRAPEL IFGATNYTNQ IDIWSSGCVM AELLLGQPMF 

       250        260        270        280        290        300 
PGESGIDQLV EIIKILGTPS KQEICSMNPN YMEHKFPQIK PIPLSRVFKK EDDQTVEFLA 

       310        320        330        340        350        360 
DVLKYDPLER FNALQCLCSP YFDELKLDDG KINQITTDLK LLEFDENVEL GHLSPDELSS 

       370 
VKKKLYPKSK 

References and documentation are available.

Number of amino acids: 370

Molecular weight: 43004.52

Theoretical pI: 6.09

Amino acid composition: 
Ala (A)  10	  2.7%
Arg (R)  12	  3.2%
Asn (N)  22	  5.9%
Asp (D)  21	  5.7%
Cys (C)   7	  1.9%
Gln (Q)  20	  5.4%
Glu (E)  25	  6.8%
Gly (G)  12	  3.2%
His (H)  10	  2.7%
Ile (I)  27	  7.3%
Leu (L)  40	 10.8%
Lys (K)  29	  7.8%
Met (M)  10	  2.7%
Phe (F)  19	  5.1%
Pro (P)  25	  6.8%
Ser (S)  26	  7.0%
Thr (T)  14	  3.8%
Trp (W)   2	  0.5%
Tyr (Y)  18	  4.9%
Val (V)  21	  5.7%
Pyl (O)   0	  0.0%
Sec (U)   0	  0.0%

 (B)   0	  0.0%
 (Z)   0	  0.0%
 (X)   0	  0.0%


Total number of negatively charged residues (Asp + Glu): 46
Total number of positively charged residues (Arg + Lys): 41

Atomic composition:

Carbon      C	      1949
Hydrogen    H	      3029
Nitrogen    N	       499
Oxygen      O	       563
Sulfur      S	        17

Formula: C1949H3029N499O563S17
Total number of atoms: 6057

Extinction coefficients:

Extinction coefficients are in units of  M-1 cm-1, at 280 nm measured in water.

Ext. coefficient    38195
Abs 0.1% (=1 g/l)   0.888, assuming all pairs of Cys residues form cystines


Ext. coefficient    37820
Abs 0.1% (=1 g/l)   0.879, assuming all Cys residues are reduced

Estimated half-life:

The N-terminal of the sequence considered is M (Met).

The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro).
                            >20 hours (yeast, in vivo).
                            >10 hours (Escherichia coli, in vivo).


Instability index:

The instability index (II) is computed to be 44.32
This classifies the protein as unstable.



Aliphatic index: 89.78

Grand average of hydropathicity (GRAVY): -0.374