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ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MNIVPQDTFK SQVSTDQDKS VLSSAVPSLP DTLRQQEGGA VPLSTQLNDR HPLESTLKNW 

        70         80         90        100        110        120 
ETTQRQRQME QYRQIFGIAE PMKRTMEMEI VNRTDFNPLS TNGSIHRDIL LNKECSIDWE 

       130        140 
DVYPGTGLQA STMVGDDVHS KIEKQLGI


References and documentation are available. 

Number of amino acids: 148

Molecular weight: 16759.80

Theoretical pI: 5.01


Amino acid composition: 
Ala (A)   4	  2.7%
Arg (R)   8	  5.4%
Asn (N)   7	  4.7%
Asp (D)  11	  7.4%
Cys (C)   1	  0.7%
Gln (Q)  13	  8.8%
Glu (E)  10	  6.8%
Gly (G)   8	  5.4%
His (H)   3	  2.0%
Ile (I)   9	  6.1%
Leu (L)  12	  8.1%
Lys (K)   7	  4.7%
Met (M)   6	  4.1%
Phe (F)   3	  2.0%
Pro (P)   8	  5.4%
Ser (S)  13	  8.8%
Thr (T)  12	  8.1%
Trp (W)   2	  1.4%
Tyr (Y)   2	  1.4%
Val (V)   9	  6.1%
Pyl (O)   0	  0.0%
Sec (U)   0	  0.0%

 (B)   0	  0.0%
 (Z)   0	  0.0%
 (X)   0	  0.0%



Total number of negatively charged residues (Asp + Glu): 21
Total number of positively charged residues (Arg + Lys): 15

Atomic composition:

Carbon      C	       721
Hydrogen    H	      1159
Nitrogen    N	       207
Oxygen      O	       238
Sulfur      S	         7

Formula: C721H1159N207O238S7
Total number of atoms: 2332

Extinction coefficients:

Extinction coefficients are in units of  M-1 cm-1, at 280 nm measured in water.

Ext. coefficient    13980
Abs 0.1% (=1 g/l)   0.834, assuming all pairs of Cys residues form cystines


Ext. coefficient    13980
Abs 0.1% (=1 g/l)   0.834, assuming all Cys residues are reduced

Estimated half-life:

The N-terminal of the sequence considered is M (Met).

The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro).
                            >20 hours (yeast, in vivo).
                            >10 hours (Escherichia coli, in vivo).


Instability index:

The instability index (II) is computed to be 42.81
This classifies the protein as unstable.



Aliphatic index: 75.68

Grand average of hydropathicity (GRAVY): -0.691