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ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MNIYIFSKEK KRKKVVCDNL SKTRGSRREH CEPHRRRMGQ STSKFRRSKT TFTSPVLPNL

70 80 90 100 110 120
REQNSGADEP YDYISNLPDE CLSLIFQSLT CADLKRCSLV CRRWLTIEGQ CRHRLSLKAQ

130 140 150 160 170 180
SDLISVIPSL FTRFDSVTKL VLRSDRRSLG ICDNAFVMIS VRCRNLTRLK LRGCPEISDL

190 200 210 220 230 240
GIIGFTENCR SLKKVSFGSC GFGVKGMNAL LNTCLGLEEL SVKRLRGIGA GAELIGPGGA

250 260 270 280 290 300
AGSLKVICLK ELHNGQCFAP LLSGAKGLRI LKIFRCSGDW DRVFEAVRDK VNAIVEIHLE

310 320 330 340 350 360
RIQMSDLGLT ALSKCSGVEV LHLVKTPDCT NVGLALVAER CKLLRKLHID GWKTNRIGDE

370 380 390 400 410 420
GLIVVAKYCW NLQELVLIGV NPTKLSLEAI VSNCLNLERL ALCGSDTVGD TELCCIAEKC

430 440 450 460 470 480
LALRKLCIKN CPITDDGIKA LGNGCPNLLK VKVKKCRGVT TQGADLLRKR RALLVVNLDA

490 500 510 520 530 540
PETPIVEGSV GEGGAQENAV EFPPSRLQIP TIGLASGSTS RSSSFKLRLG FLSQRNFVSC

550
ALRRLGSRSR SRNE


References and documentation are available.

Number of amino acids: 554 Molecular weight: 61005.36 Theoretical pI: 9.50
Amino acid composition: 
Ala (A) 29 5.2% Arg (R) 49 8.8% Asn (N) 25 4.5% Asp (D) 23 4.2% Cys (C) 30 5.4% Gln (Q) 12 2.2% Glu (E) 30 5.4% Gly (G) 46 8.3% His (H) 7 1.3% Ile (I) 32 5.8% Leu (L) 76 13.7% Lys (K) 38 6.9% Met (M) 5 0.9% Phe (F) 17 3.1% Pro (P) 18 3.2% Ser (S) 47 8.5% Thr (T) 25 4.5% Trp (W) 4 0.7% Tyr (Y) 4 0.7% Val (V) 37 6.7% Pyl (O) 0 0.0% Sec (U) 0 0.0% (B) 0 0.0% (Z) 0 0.0% (X) 0 0.0%
Total number of negatively charged residues (Asp + Glu): 53 Total number of positively charged residues (Arg + Lys): 87 Atomic composition: Carbon C 2657 Hydrogen H 4430 Nitrogen N 794 Oxygen O 774 Sulfur S 35 Formula: C2657H4430N794O774S35 Total number of atoms: 8690 Extinction coefficients: Extinction coefficients are in units of M-1 cm-1, at 280 nm measured in water. Ext. coefficient 29835 Abs 0.1% (=1 g/l) 0.489, assuming all pairs of Cys residues form cystines Ext. coefficient 27960 Abs 0.1% (=1 g/l) 0.458, assuming all Cys residues are reduced Estimated half-life: The N-terminal of the sequence considered is M (Met). The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro). >20 hours (yeast, in vivo). >10 hours (Escherichia coli, in vivo). Instability index: The instability index (II) is computed to be 47.06 This classifies the protein as unstable. Aliphatic index: 100.63 Grand average of hydropathicity (GRAVY): -0.081