ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MNKDQAEKYQ ERSLRQKYNL LHVLPTLNSR ALSGLYYKNF HNSVKRYQIM LPEQLKSGKF 

        70         80         90        100        110        120 
CSHCGCVYVP NFNASLQLTT NTEQGDSDEL GGESMEGPKK CIQVNCLNCE KSKLFEWKSE 

       130        140        150        160        170        180 
FVVPTFGQDV SPMINSTSSG KVSYAVKKPQ KSKTSTGKER SKKRKLNSLT NLLSKRNQEK 

       190 
KMEKKKSSSL SLESFMKS 

References and documentation are available.

Number of amino acids: 198

Molecular weight: 22540.86

Theoretical pI: 9.66

Amino acid composition: 
Ala (A)   4	  2.0%
Arg (R)   7	  3.5%
Asn (N)  14	  7.1%
Asp (D)   4	  2.0%
Cys (C)   6	  3.0%
Gln (Q)  11	  5.6%
Glu (E)  14	  7.1%
Gly (G)  10	  5.1%
His (H)   3	  1.5%
Ile (I)   3	  1.5%
Leu (L)  20	 10.1%
Lys (K)  28	 14.1%
Met (M)   6	  3.0%
Phe (F)   7	  3.5%
Pro (P)   7	  3.5%
Ser (S)  27	 13.6%
Thr (T)   9	  4.5%
Trp (W)   1	  0.5%
Tyr (Y)   7	  3.5%
Val (V)  10	  5.1%
Pyl (O)   0	  0.0%
Sec (U)   0	  0.0%

 (B)   0	  0.0%
 (Z)   0	  0.0%
 (X)   0	  0.0%


Total number of negatively charged residues (Asp + Glu): 18
Total number of positively charged residues (Arg + Lys): 35

Atomic composition:

Carbon      C	       982
Hydrogen    H	      1593
Nitrogen    N	       279
Oxygen      O	       303
Sulfur      S	        12

Formula: C982H1593N279O303S12
Total number of atoms: 3169

Extinction coefficients:

Extinction coefficients are in units of  M-1 cm-1, at 280 nm measured in water.

Ext. coefficient    16305
Abs 0.1% (=1 g/l)   0.723, assuming all pairs of Cys residues form cystines


Ext. coefficient    15930
Abs 0.1% (=1 g/l)   0.707, assuming all Cys residues are reduced

Estimated half-life:

The N-terminal of the sequence considered is M (Met).

The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro).
                            >20 hours (yeast, in vivo).
                            >10 hours (Escherichia coli, in vivo).


Instability index:

The instability index (II) is computed to be 41.92
This classifies the protein as unstable.



Aliphatic index: 61.97

Grand average of hydropathicity (GRAVY): -0.855