ProtParam
User-provided sequence:
10 20 30 40 50 60
MNNTDPTSFE SILAGVAKLR KEKSGADTTG SQSLEIDASK LQQQEPQTSR RINSNQVINA
70 80 90 100 110 120
FNQQKPEEWT DSKATDDYNR KRPFRSTRPG KTVLVNTTQK ENPLLNHLKS TNWRYVSSTG
130 140 150 160 170 180
INMIYYDYLV RGRSVLFLTL TYHKLYVDYI SRRMQPLSRN ENNILIFIVD DNNSEDTLND
190 200 210
ITKLCMFNGF TLLLAFNFEQ AAKYIEYLNL
References and
documentation are available.
Number of amino acids: 210
Molecular weight: 24311.36
Theoretical pI: 8.87
Total number of negatively charged residues (Asp + Glu): 23
Total number of positively charged residues (Arg + Lys): 26
Atomic composition:
Carbon C 1074
Hydrogen H 1692
Nitrogen N 300
Oxygen O 334
Sulfur S 5
Formula: C
1074H
1692N
300O
334S
5
Total number of atoms: 3405
Extinction coefficients:
Extinction coefficients are in units of M
-1 cm
-1, at 280 nm measured in water.
Ext. coefficient 25900
Abs 0.1% (=1 g/l) 1.065, assuming all pairs of Cys residues form cystines
Ext. coefficient 25900
Abs 0.1% (=1 g/l) 1.065, assuming all Cys residues are reduced
Estimated half-life:
The N-terminal of the sequence considered is M (Met).
The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro).
>20 hours (yeast, in vivo).
>10 hours (Escherichia coli, in vivo).
Instability index:
The instability index (II) is computed to be 43.29
This classifies the protein as unstable.
Aliphatic index: 79.86
Grand average of hydropathicity (GRAVY): -0.649