ProtParam
User-provided sequence:
10 20 30 40 50 60
MNPKSSTPKI PRPKNAFILF RQHYHRILID EWTAQGVEIP HNSNISKIIG TKWKGLQPED
70 80 90 100 110 120
KAHWENLAEK EKLEHERKYP EYKYKPVRKS KKKQLLLKEI EQQQQQQQKE QQQQKQSQPQ
130 140 150 160 170 180
LQQPFNNNIV LMKRAHSLSP SSSVSSSNSY QFQLNNDLKR LPIPSVNTSN YMVSRSLSGL
190 200 210 220 230 240
PLTHDKTARD LPQLSSQLNS IPYYSAPHDP STRHHYLNVA QAQPRANSTP QLPFISSIIN
250 260 270 280 290 300
NSSQTPVTTT TTSTTTATSS PGKFSSSPNS SVLENNRLNS INNSNQYLPP PLLPSLQDFQ
310 320 330 340 350 360
LDQYQQLKQM GPTYIVKPLS HTRNNLLSTT TPTHHHIPHI PNQNIPLHQI INSSNTEVTA
KTSLVSPK
References and
documentation are available.
Number of amino acids: 368
Molecular weight: 41838.08
Theoretical pI: 9.88
Total number of negatively charged residues (Asp + Glu): 22
Total number of positively charged residues (Arg + Lys): 40
Atomic composition:
Carbon C 1845
Hydrogen H 2933
Nitrogen N 537
Oxygen O 567
Sulfur S 4
Formula: C
1845H
2933N
537O
567S
4
Total number of atoms: 5886
Extinction coefficients:
Extinction coefficients are in units of M
-1 cm
-1, at 280 nm measured in water.
Ext. coefficient 34380
Abs 0.1% (=1 g/l) 0.822
Estimated half-life:
The N-terminal of the sequence considered is M (Met).
The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro).
>20 hours (yeast, in vivo).
>10 hours (Escherichia coli, in vivo).
Instability index:
The instability index (II) is computed to be 62.23
This classifies the protein as unstable.
Aliphatic index: 73.12
Grand average of hydropathicity (GRAVY): -0.902