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ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MNPSAPSYPM ASLYVGDLHP DVTEAMLYEK FSPAGPILSI RVCRDMITRR SLGYAYVNFQ

70 80 90 100 110 120
QPADAERALD TMNFDVIKGK PVRIMWSQRD PSLRKSGVGN IFIKNLDKSI DNKALYDTFS

130 140 150 160 170 180
AFGNILSCKV VCDENGSKGY GFVHFETQEA AERAIEKMNG MLLNDRKVFV GRFKSRKERE

190 200 210 220 230 240
AELGARAKEF TNVYIKNFGE DMDDERLKDL FGKFGPALSV KVMTDESGKS KGFGFVSFER

250 260 270 280 290 300
HEDAQKAVDE MNGKELNGKQ IYVGRAQKKV ERQTELKRKF EQMKQDRITR YQGVNLYVKN

310 320 330 340 350 360
LDDGIDDERL RKEFSPFGTI TSAKVMMEGG RSKGFGFVCF SSPEEATKAV TEMNGRIVAT

370 380 390 400 410 420
KPLYVALAQR KEERQAHLTN QYMQRMASVR AVPNPVINPY QPAPPSGYFM AAIPQTQNRA

430 440 450 460 470 480
AYYPPSQIAQ LRPSPRWTAQ GARPHPFQNM PGAIRPAAPR PPFSTMRPAS SQVPRVMSTQ

490 500 510 520 530 540
RVANTSTQTM GPRPAAAAAA ATPAVRTVPQ YKYAAGVRNP QQHLNAQPQV TMQQPAVHVQ

550 560 570 580 590 600
GQEPLTASML ASAPPQEQKQ MLGERLFPLI QAMHPTLAGK ITGMLLEIDN SELLHMLESP

610 620 630
ESLRSKVDEA VAVLQAHQAK EAAQKAVNSA TGVPTV


References and documentation are available.

Number of amino acids: 636 Molecular weight: 70670.84 Theoretical pI: 9.52
Amino acid composition: 
Ala (A) 67 10.5% Arg (R) 43 6.8% Asn (N) 27 4.2% Asp (D) 26 4.1% Cys (C) 4 0.6% Gln (Q) 41 6.4% Glu (E) 39 6.1% Gly (G) 40 6.3% His (H) 10 1.6% Ile (I) 23 3.6% Leu (L) 39 6.1% Lys (K) 41 6.4% Met (M) 28 4.4% Phe (F) 27 4.2% Pro (P) 47 7.4% Ser (S) 39 6.1% Thr (T) 30 4.7% Trp (W) 2 0.3% Tyr (Y) 19 3.0% Val (V) 44 6.9% Pyl (O) 0 0.0% Sec (U) 0 0.0% (B) 0 0.0% (Z) 0 0.0% (X) 0 0.0%
Total number of negatively charged residues (Asp + Glu): 65 Total number of positively charged residues (Arg + Lys): 84 Atomic composition: Carbon C 3109 Hydrogen H 4946 Nitrogen N 896 Oxygen O 923 Sulfur S 32 Formula: C3109H4946N896O923S32 Total number of atoms: 9906 Extinction coefficients: Extinction coefficients are in units of M-1 cm-1, at 280 nm measured in water. Ext. coefficient 39560 Abs 0.1% (=1 g/l) 0.560, assuming all pairs of Cys residues form cystines Ext. coefficient 39310 Abs 0.1% (=1 g/l) 0.556, assuming all Cys residues are reduced Estimated half-life: The N-terminal of the sequence considered is M (Met). The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro). >20 hours (yeast, in vivo). >10 hours (Escherichia coli, in vivo). Instability index: The instability index (II) is computed to be 41.87 This classifies the protein as unstable. Aliphatic index: 68.62 Grand average of hydropathicity (GRAVY): -0.511