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ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MNQEDNTGGG GIFGLFKWTK DALFGTDISP SMKYKDQEER RDRSRYAQDD TNFSMKFGND

70 80 90 100 110 120
SNRRSTNLSR SNSWSGLDST LHRKYELLPE YNENGFNSIV NGDHHSKERI RSLRSPAPIV

130 140 150 160 170 180
PREPLRNEPT DTFGHRLHTK RRTINELSNS QIPFIPPQED DPLLSKLFNK DGVNEVRRSP

190 200 210 220 230 240
YKLSVKDIPG KFPSPLTKRD EIDNYYVRDE DACHKNREYK KAYFDLFAQM DLNSRDLEDL

250 260 270 280 290 300
CEDVREQREQ FHRNEQTYKQ AYEEMRAELV NELKKSKTLF ENYYSLGQKY KSLKKVLDQT

310 320 330 340 350 360
ISHEAELATS RERLYQEEDL KNFEIQTLKQ RLSDLELKYT NLQIEKDMQR DNYESEIHDL

370 380
LLQLSLRNNE RKDTSAGSNI FSTGQ


References and documentation are available.

Number of amino acids: 385 Molecular weight: 45384.31 Theoretical pI: 6.08
Amino acid composition: 
Ala (A) 11 2.9% Arg (R) 32 8.3% Asn (N) 28 7.3% Asp (D) 31 8.1% Cys (C) 2 0.5% Gln (Q) 19 4.9% Glu (E) 36 9.4% Gly (G) 16 4.2% His (H) 9 2.3% Ile (I) 15 3.9% Leu (L) 39 10.1% Lys (K) 30 7.8% Met (M) 6 1.6% Phe (F) 16 4.2% Pro (P) 15 3.9% Ser (S) 33 8.6% Thr (T) 19 4.9% Trp (W) 2 0.5% Tyr (Y) 17 4.4% Val (V) 9 2.3% Pyl (O) 0 0.0% Sec (U) 0 0.0% (B) 0 0.0% (Z) 0 0.0% (X) 0 0.0%
Total number of negatively charged residues (Asp + Glu): 67 Total number of positively charged residues (Arg + Lys): 62 Atomic composition: Carbon C 1976 Hydrogen H 3098 Nitrogen N 578 Oxygen O 636 Sulfur S 8 Formula: C1976H3098N578O636S8 Total number of atoms: 6296 Extinction coefficients: Extinction coefficients are in units of M-1 cm-1, at 280 nm measured in water. Ext. coefficient 36455 Abs 0.1% (=1 g/l) 0.803, assuming all pairs of Cys residues form cystines Ext. coefficient 36330 Abs 0.1% (=1 g/l) 0.800, assuming all Cys residues are reduced Estimated half-life: The N-terminal of the sequence considered is M (Met). The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro). >20 hours (yeast, in vivo). >10 hours (Escherichia coli, in vivo). Instability index: The instability index (II) is computed to be 53.99 This classifies the protein as unstable. Aliphatic index: 64.34 Grand average of hydropathicity (GRAVY): -1.164