ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MNRDNMDTTK RKEDHTKHTT DVIEFYEEGT AASSLNIATE KANSSPSILR RIINRAAWLS 

        70         80         90        100        110        120 
KKVDAMGVES TGIQRISPYE RGTSKKQFLH VAGLWLSATG GLSSMSSFLL GPLLFGLSFR 

       130        140        150        160        170        180 
ESVASSLISV TIGCLIAAYC SIMGPQSGCR QMVTARYLFG WWFVKLVALA SIIGVMGWSV 

       190        200        210        220        230        240 
VNSVVGGEML AAISNDKVPL WVGIVIVTVC SFLVAIFGIK QVIKVETYLS VPVLTAFLLL 

       250        260        270        280        290        300 
YISSSDKYSF VNAYVSKGNL DSSTRKGNWM SFFSLCYSIT ATWGSITADY YILFPEDTPY 

       310        320        330        340        350        360 
IQIFCLTFFG TFLPTCFVGI LGLLLASVAM SYKPWSVEYD SHGMGGLLWA GFQRWNGFGK 

       370        380        390        400        410        420 
FCVVVLVFSL VSNNIINTYS AAFSIQLSSV FCAKIPRWFW SIVCTIICLV CALIGRNHFS 

       430        440        450        460        470        480 
TILGNFLPMI GYWISMYFIL LFEENLVFRR FFLHLYTKEF PTVTGEINGP ELVGSSKEVE 

       490        500        510        520        530        540 
KDAVTNIHLL KRKHKVTKHR YNWDKWEDYE VLTHGYAATF AFIVGVAGVV VGMAQAYWIG 

       550        560        570 
PIAAKFGEYG GDVAMWLSMA FSGVVYPPCR YLELRKFGR 

References and documentation are available.

Number of amino acids: 579

Molecular weight: 64546.35

Theoretical pI: 8.92

Amino acid composition: 
Ala (A)  40	  6.9%
Arg (R)  21	  3.6%
Asn (N)  20	  3.5%
Asp (D)  15	  2.6%
Cys (C)  13	  2.2%
Gln (Q)   9	  1.6%
Glu (E)  23	  4.0%
Gly (G)  47	  8.1%
His (H)  10	  1.7%
Ile (I)  43	  7.4%
Leu (L)  55	  9.5%
Lys (K)  28	  4.8%
Met (M)  16	  2.8%
Phe (F)  39	  6.7%
Pro (P)  17	  2.9%
Ser (S)  55	  9.5%
Thr (T)  33	  5.7%
Trp (W)  18	  3.1%
Tyr (Y)  25	  4.3%
Val (V)  52	  9.0%
Pyl (O)   0	  0.0%
Sec (U)   0	  0.0%

 (B)   0	  0.0%
 (Z)   0	  0.0%
 (X)   0	  0.0%


Total number of negatively charged residues (Asp + Glu): 38
Total number of positively charged residues (Arg + Lys): 49

Atomic composition:

Carbon      C	      2991
Hydrogen    H	      4565
Nitrogen    N	       737
Oxygen      O	       798
Sulfur      S	        29

Formula: C2991H4565N737O798S29
Total number of atoms: 9120

Extinction coefficients:

Extinction coefficients are in units of  M-1 cm-1, at 280 nm measured in water.

Ext. coefficient   137000
Abs 0.1% (=1 g/l)   2.123, assuming all pairs of Cys residues form cystines


Ext. coefficient   136250
Abs 0.1% (=1 g/l)   2.111, assuming all Cys residues are reduced

Estimated half-life:

The N-terminal of the sequence considered is M (Met).

The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro).
                            >20 hours (yeast, in vivo).
                            >10 hours (Escherichia coli, in vivo).


Instability index:

The instability index (II) is computed to be 32.93
This classifies the protein as stable.



Aliphatic index: 98.96

Grand average of hydropathicity (GRAVY): 0.402