ProtParam
User-provided sequence:
10 20 30 40 50 60
MNSEQLLHNY VSDSLLTTLI SFQEFKQQLQ SYTSDEQQLQ HWYELLQARD ARVTSELEAR
70 80 90 100 110 120
IKQFFITLRS RLLRFLESEQ LSHSLSLETL IDALYKINDL LQQRLQILDD AIQEKTSELA
130 140 150
EFENMVRSPS AGDNAIPGLL QIIQSYINLL EEN
References and
documentation are available.
Number of amino acids: 153
Molecular weight: 17862.13
Theoretical pI: 4.59
Total number of negatively charged residues (Asp + Glu): 23
Total number of positively charged residues (Arg + Lys): 12
Atomic composition:
Carbon C 793
Hydrogen H 1262
Nitrogen N 212
Oxygen O 252
Sulfur S 2
Formula: C
793H
1262N
212O
252S
2
Total number of atoms: 2521
Extinction coefficients:
Extinction coefficients are in units of M
-1 cm
-1, at 280 nm measured in water.
Ext. coefficient 12950
Abs 0.1% (=1 g/l) 0.725
Estimated half-life:
The N-terminal of the sequence considered is M (Met).
The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro).
>20 hours (yeast, in vivo).
>10 hours (Escherichia coli, in vivo).
Instability index:
The instability index (II) is computed to be 63.21
This classifies the protein as unstable.
Aliphatic index: 110.33
Grand average of hydropathicity (GRAVY): -0.335